CAJ | 학술논문

目的：探讨乌贝散方剂联合三联疗法对胃溃疡患者的治疗效果。方法：选择147例胃溃疡患者作为研究对象，随机分为治疗组（74例）和对照组（73例），对照组给予西医三联疗法，观察组给予乌贝散方剂联合三联疗法，疗程均为2周，观察两组患者的疗效，Hp消除率及不良反应的发生率。结果：治疗组患者治疗总有效率（68例，91.9%）和Hp清除率（69例，93.2%）均明显高于对照组（分别为79.5%和82.2%），差异有统计学意义（P＜0.05）；治疗组患者不良反应发生率（4例，5.4%）与对照组（6例，8.2%）的差异无统计学意义（P＞0.05）。结论：乌贝散方剂联合三联疗法可有效清除Hp，对胃溃疡患者的治疗效果较好，且不良反应少。
목적：탐토오패산방제연합삼련요법대위궤양환자적치료효과。방법：선택147례위궤양환자작위연구대상，수궤분위치료조（74례）화대조조（73례），대조조급여서의삼련요법，관찰조급여오패산방제연합삼련요법，료정균위2주，관찰량조환자적료효，Hp소제솔급불량반응적발생솔。결과：치료조환자치료총유효솔（68례，91.9%）화Hp청제솔（69례，93.2%）균명현고우대조조（분별위79.5%화82.2%），차이유통계학의의（P＜0.05）；치료조환자불량반응발생솔（4례，5.4%）여대조조（6례，8.2%）적차이무통계학의의（P＞0.05）。결론：오패산방제연합삼련요법가유효청제Hp，대위궤양환자적치료효과교호，차불량반응소。
Objective: To explore the clinical effect of Wu Beisan powder combined with western therapy in the treatment of gastric ulcer. Methods: 147 patients with gastric ulcer were selected and divided into a treatment group (74 cases) and a control group (73 cases). The patients in control group were treated with western triple therapy, while the patients in treatment group were treated with Wu Beisan Powder combined with western triple therapy. All patients were treated for 2 weeks. The efficacy, Helicobacterpylori (Hp) clearance and the incidence of adverse reactions in two groups were observed. Results: The total effective rate in treatment group (68 cases, 91.9%) was significantly higher than that of the control group (58 cases, 79.5%), and the Hp clearance rate in treatment group (69 cases, 93.2%) was also significantly higher than that of the control group (60 cases, 82.2%) (P<0.05). The incidence of adverse reactions in the treatment group (4 cases, 5.4%) was significantly less than that of the control group (6 cases, 8.2%) (P<0.05). Conclusions: Wu Beisan Powder combined with western triple therapy can effectively remove Hp and has better effect on gastric ulcer with less adverse reactions.