CAJ | 학술논문

目的：研究岭南地区溃疡性结肠炎的中医证候分别与结肠镜像分型、黏膜组织学分期的相关性，为中医辨证提供客观依据。方法收集岭南地区溃疡性结肠炎患者124例，统计不同证候所占比例，分析中医证型与结肠镜像分型、黏膜组织学分期各自的相关性。结果岭南地区溃疡性结肠炎临床以大肠湿热、脾虚湿热、脾胃气虚三类证型多见。结肠镜像分型Ⅰ型以大肠湿热证多见，脾虚湿热证、脾胃气虚证少见(P<0.05)；Ⅱ型三证出现的概率相当；Ⅲ型以脾胃气虚证、脾虚湿热证多见，大肠湿热证少见(P<0.05)。黏膜组织学分期活动期多见于大肠湿热证，与脾虚湿热证、脾胃气虚证比较，差异均有统计学意义(P<0.05)；缓解期多见于脾虚湿热证、脾胃气虚证，与大肠湿热证比较，差异均有统计学意义(P<0.05)。结论岭南地区溃疡性结肠炎的中医证候与结肠镜像分型、黏膜组织学分期有明显的相关性，结肠镜及病理组织学检查可作为中医辨证的客观化指标。
목적：연구령남지구궤양성결장염적중의증후분별여결장경상분형、점막조직학분기적상관성，위중의변증제공객관의거。방법수집령남지구궤양성결장염환자124례，통계불동증후소점비례，분석중의증형여결장경상분형、점막조직학분기각자적상관성。결과령남지구궤양성결장염림상이대장습열、비허습열、비위기허삼류증형다견。결장경상분형Ⅰ형이대장습열증다견，비허습열증、비위기허증소견(P<0.05)；Ⅱ형삼증출현적개솔상당；Ⅲ형이비위기허증、비허습열증다견，대장습열증소견(P<0.05)。점막조직학분기활동기다견우대장습열증，여비허습열증、비위기허증비교，차이균유통계학의의(P<0.05)；완해기다견우비허습열증、비위기허증，여대장습열증비교，차이균유통계학의의(P<0.05)。결론령남지구궤양성결장염적중의증후여결장경상분형、점막조직학분기유명현적상관성，결장경급병리조직학검사가작위중의변증적객관화지표。
Objective To study the relationship between traditional Chinese medicine (TCM) syndrome of ulcerative colitis in Lingnan area and endoscopic classification and mucosal tissue staging, providing the objective basis for the TCM differentiation. Methods A total of 124 patients with ulcerative colitis in Lingnan area were selected. The pro-portions of different clinical TCM syndrome type were analyzed, and the correlations between TCM syndrome type and endoscopic classification and mucosal tissue staging were analyzed. Results The common types of TCM syn-drome of ulcerative colitis in Lingnan area were large intestine damp-heat, spleen-deficiency and dampness-heat, defi-ciency of spleen and stomach qi. TypeⅠendoscopic classification was showed more in large intestine damp-heat than in spleen-deficiency and dampness-heat, deficiency of spleen and stomach qi (P<0.05). There was similar probability of TypeⅡendoscopic classification in the three TCM syndrome types. TypeⅢ endoscopic classification was signifi-cantly less showed in large intestine damp-heat than in spleen-deficiency and dampness-heat, deficiency of spleen and stomach qi (P<0.05). Large intestine damp-heat was the most common in the active phase of mucosal tissue staging (P<0.05), while spleen-deficiency and dampness-heat as well as deficiency of spleen and stomach qi occupied main positions in the relieving phase of mucosal tissue staging (P<0.05). Conclusion The TCM syndrome of ulcerative colitis in Lingnan area has an significant relationship between endoscopic classification and mucosal tissue staging, and endoscopic classification and mucosal tissue staging may provide objective basis for the TCM differentiation.