CAJ | 학술논문

目的：探讨慢性阻塞性肺疾病（COPD）患者肺功能及呼吸困难程度与体质量指数（BMI）的相关性，为BMI用于COPD患者的诊断及病情评估提供参考依据。方法将156例COPD稳定期患者随机分为低BMI组、正常BMI组和高BMI组，分别进行肺功能检测和采用6MWT评估呼吸困难程度，分析BMI与肺功能及呼吸困难程度的相关性。结果（1）高低BMI两组FVC、FEV1%和FEV1/FVC均低于正常BMI组，三组FVC、FEV1%比较有统计学差异（P＜0.05）；而三组FEV1/FVC比较无统计学差异统计学（P＞0.05）。（2）低BMI组和高BMI组在6min步行试验中有统计学差异（P＜0.05），且低BMI组在重度和极重度中比例均明显高于高BMI组。结论 COPD患者体质量指数与肺功能及呼吸困难程度存在密切相关性，可为COPD患者的病情评估、后续辅助治疗及判断预后提供一定的参考依据。
목적：탐토만성조새성폐질병（COPD）환자폐공능급호흡곤난정도여체질량지수（BMI）적상관성，위BMI용우COPD환자적진단급병정평고제공삼고의거。방법장156례COPD은정기환자수궤분위저BMI조、정상BMI조화고BMI조，분별진행폐공능검측화채용6MWT평고호흡곤난정도，분석BMI여폐공능급호흡곤난정도적상관성。결과（1）고저BMI량조FVC、FEV1%화FEV1/FVC균저우정상BMI조，삼조FVC、FEV1%비교유통계학차이（P＜0.05）；이삼조FEV1/FVC비교무통계학차이통계학（P＞0.05）。（2）저BMI조화고BMI조재6min보행시험중유통계학차이（P＜0.05），차저BMI조재중도화겁중도중비례균명현고우고BMI조。결론 COPD환자체질량지수여폐공능급호흡곤난정도존재밀절상관성，가위COPD환자적병정평고、후속보조치료급판단예후제공일정적삼고의거。
Objective To explore the relationship between lung function, dyspnea and body mass index(BMI) in patients with chronic obstructive pulmonary disease(COPD),to provide evidence for diagnosis and assessment of the condition in patients with COPD with BMI.Methods156 patients were randomized into low BMI group, normal BMI group and high BMI group, the pulmonary function test was performed, and dyspnea was measured with 6MWT, the relationship between BMI,lung function and dyspnea were analyzed.Results (1)The FVC,FEV1 and FEV1/FVC of low BMI group and high BMI group were lower than normal BMI group, the FVC and FEV1 of three groups were significant difference (P<0.05); the FEV1/FVC of three groups were no significant difference (P>0.05). (2) The differences of 6MWT were significant difference between low BMI group and high BMI group(P<0.05), and the severe-to-very severe proportion of low BMI group was higher than high BMI group.Conclusion The relationship between lung function, dyspnea and BMI in patients with chronic obstructive pulmonary disease, which should provide the reference of assessment of the condition, evidence for diagnosis and prognosis in patients with COPD.