CAJ | 학술논문

目的：活体观察长期2型糖尿病小鼠视网膜血管的损害。方法：应用荧光眼底血管造影（FFA）活体观察视网膜血管，对长期2型糖尿病小鼠视网膜血管数量及渗漏状态进行综合评价。结果：眼底照相显示长期2型糖尿病小鼠视网膜可见动脉反光增强，静脉迂曲扩张，未见明显荧光素渗漏，但可见毛细血管网密度降低。结论：2型糖尿病小鼠的视网膜血管损害主要表现为血管退行性变，而非血管的渗漏。
목적：활체관찰장기2형당뇨병소서시망막혈관적손해。방법：응용형광안저혈관조영（FFA）활체관찰시망막혈관，대장기2형당뇨병소서시망막혈관수량급삼루상태진행종합평개。결과：안저조상현시장기2형당뇨병소서시망막가견동맥반광증강，정맥우곡확장，미견명현형광소삼루，단가견모세혈관망밀도강저。결론：2형당뇨병소서적시망막혈관손해주요표현위혈관퇴행성변，이비혈관적삼루。
Objective: To observe the damage of retinal blood vessels in mice with long-term type 2 diabetes. Methods: The retinal blood vessels were observed by fluorescence fundus angiography (FFA) and the number and situation of the retinal blood vessels and leakage of type 2 diabetic mice were observed and evaluated. Results: The fundus photography showed that the visibility of type 2 diabetic mice retinal arteries was enhanced and vein dilated, but no obvious fluorescein leakage. Conclusion: The main manifestation of type 2 diabetic mice is retinal vascular damage, not the blood vessels.