CAJ | 학술논문

目的：探讨在双腔耐高压经外周置入中心静脉导管（PICC）连接输液泵持续泵入化疗药物期间，不同冲管频次对PICC并发症的影响。方法将160例双腔耐高压PICC连接输液泵持续泵入化疗药物的恶性淋巴瘤患者按照随机数字表法分为4组，每组40例：A组每4小时冲管1次；B组每8小时冲管1次；C组每12小时冲管1次；D组每24小时冲管1次。观察4组导管堵塞、静脉炎发生率。结果采取不同的冲管频次对双腔耐高压PICC连接输液泵持续化疗期间导管堵塞发生率不同：A组为0；B组为2.5%（1/40）；C组为27.5%（11/40）；D组高达42.5%（17/40），组间比较差异有统计学意义，χ2=30.870，P＜0.01；4组患者静脉炎发生率比较差异无统计学意义，P＞0.05。结论双腔耐高压PICC连接输液泵持续化疗期间应严格执行每8小时冲管1次，既降低了导管堵塞的发生率，又未增加静脉炎的发生率，值得临床推广应用。
목적：탐토재쌍강내고압경외주치입중심정맥도관（PICC）련접수액빙지속빙입화료약물기간，불동충관빈차대PICC병발증적영향。방법장160례쌍강내고압PICC련접수액빙지속빙입화료약물적악성림파류환자안조수궤수자표법분위4조，매조40례：A조매4소시충관1차；B조매8소시충관1차；C조매12소시충관1차；D조매24소시충관1차。관찰4조도관도새、정맥염발생솔。결과채취불동적충관빈차대쌍강내고압PICC련접수액빙지속화료기간도관도새발생솔불동：A조위0；B조위2.5%（1/40）；C조위27.5%（11/40）；D조고체42.5%（17/40），조간비교차이유통계학의의，χ2=30.870，P＜0.01；4조환자정맥염발생솔비교차이무통계학의의，P＞0.05。결론쌍강내고압PICC련접수액빙지속화료기간응엄격집행매8소시충관1차，기강저료도관도새적발생솔，우미증가정맥염적발생솔，치득림상추엄응용。
Objective To explore the effect of wash pipe frequency on complications of double-lumen power peripherally inserted central catheter (PICC) connected to infusion pump during continuous chemotherapy. Methods A total of 160 patients with malignant lymphoma whose PICC connected to infusion pump were divided into 4 groups by random digits table method with 40 cases each: flushing and sealing the tube once every 4 hours(group A), every 8 hours(group B), every 12 hours(group C) and every 24 hours (group D). The incidence of blocking pipe and phlebitis were observed. Results The incidence of blocking pipe were 0,2.5%(1/40) , 27.5%(11/40), 42.5%(17/40) in group A, B, C, D, the differences among them were significant, χ2= 30.870, P<0.01. There was no significant difference in the incidence of phlebitis among 4 groups, P>0.05. Conclusions Flushing and sealing the tube of PICC connected to infusion pump once every 8 hours during continuous chemotherapy seems to be appropriate and worthy of being applied clinically due to its low blocking pipe incidence, and low incidence of phlebitis.