CAJ | 학술논문

目的：探讨全髋关节置换术中关节内注射氨甲环酸预防术后失血的效果。方法将58例全髋关节置换患者随机分为两组，每组29例。试验组缝皮后关节腔注射氨甲环酸(1 g溶于10 ml生理盐水)，对照组注射生理盐水10 ml。观察术后血红蛋白浓度、引流量、输血率、输血量及并发症。结果与对照组比较，试验组手术前后血红蛋白差值少(P<0．01)，术后引流量、输血量和输血率均降低(P<0．01)，两组术后并发症无统计学意义(P>0．05)。结论氨甲环酸能有效减少术后出血，但并不增加并发症发生率。
목적：탐토전관관절치환술중관절내주사안갑배산예방술후실혈적효과。방법장58례전관관절치환환자수궤분위량조，매조29례。시험조봉피후관절강주사안갑배산(1 g용우10 ml생리염수)，대조조주사생리염수10 ml。관찰술후혈홍단백농도、인류량、수혈솔、수혈량급병발증。결과여대조조비교，시험조수술전후혈홍단백차치소(P<0．01)，술후인류량、수혈량화수혈솔균강저(P<0．01)，량조술후병발증무통계학의의(P>0．05)。결론안갑배산능유효감소술후출혈，단병불증가병발증발생솔。
Objective To discuss the effect of using tranexamic acid for prevention of postoperative intra-articular hemorrhage in total hip arthroplasty. Methods 58 patients with total hip arthroplasty were randomly divided into two groups, 29 cases in each group, the experimental group after skin closure intra-articular injection of tranexamic acid 1g/10ml saline,and the control group injected with saline 10ml. Postoperative hemoglobin concentration, drainage, transfusion rate, blood transfusion and complications were obscured. Results Compared with the control group,the reduce of hemoglobin difference preoperative and postoperative in the experimental group was lower(P<0. 01), blood transfusion and transfusion rate decreased(P<0. 01), and no significant difference in postoperative complications(P>0. 05). Conclusions Tranexamic acid can effectively reduce postoperative bleeding, but does not increase the in-cidence of complications.