CAJ | 학술논문

目的：评估术中聚维酮碘溶液联合生理盐水冲洗在预防脊柱手术后切口感染的有效性。方法426例脊柱手术患者纳入研究对象,分为聚维酮碘溶液联合生理盐水冲洗组( n=209)及单纯生理盐水冲洗组(n=217),术中分别行聚维酮碘溶液联合生理盐水冲洗及单纯生理盐水冲洗,分别计算术后感染率并进行统计学分析。结果聚维酮碘溶液联合生理盐水冲洗组209例中无感染发生；单纯生理盐水冲洗组217例中发生浅部感染1例(感染率0．46%)、深部感染4例(感染率1．84%)、全层感染5例(感染率2.3%),总感染率为4．6%。两组浅部感染率比较差异无统计学意义(P=0．378),两组深部感染率及全层感染率比较差异有统计学意义(P=0.016,P=0．007)。结论在脊柱外科手术中应用聚维酮碘溶液联合生理盐水进行冲洗,能有效地降低术后切口浅部及深部感染的发生率。
목적：평고술중취유동전용액연합생리염수충세재예방척주수술후절구감염적유효성。방법426례척주수술환자납입연구대상,분위취유동전용액연합생리염수충세조( n=209)급단순생리염수충세조(n=217),술중분별행취유동전용액연합생리염수충세급단순생리염수충세,분별계산술후감염솔병진행통계학분석。결과취유동전용액연합생리염수충세조209례중무감염발생；단순생리염수충세조217례중발생천부감염1례(감염솔0．46%)、심부감염4례(감염솔1．84%)、전층감염5례(감염솔2.3%),총감염솔위4．6%。량조천부감염솔비교차이무통계학의의(P=0．378),량조심부감염솔급전층감염솔비교차이유통계학의의(P=0.016,P=0．007)。결론재척주외과수술중응용취유동전용액연합생리염수진행충세,능유효지강저술후절구천부급심부감염적발생솔。
Objective To assess the effectiveness of povidone-iodine solution combined with normal saline irrigation in preventing postoperative infections of spinal surgery. Methods A total of 426 cases undergoing spinal surgery were studied and assigned to two groups according to irrigation methods. In group 1 (209 patients), surgical wounds were irrigated with povidone-iodine solution combined with normal saline in the course of spinal surgery, but povi-done-iodine solution irrigation was not used in group 2 (217 patients). The rate of infection was calculated respec-tively and statistical analysis was performed. Results There was no wound infection occurred in group 1. One surp-erfical infection(0. 46%), four deep infections (1. 84%), five whole layer infections(2. 3%) occurred in group 2 and the rate of total infection was 4. 6%. There was no statistical significance between the rate of superficial infection of the two groups(P=0. 378),but there was statistical significance between the rate of deep and whole layer infection (P=0. 016, P=0. 007). Conclusions The application of povidone-iodine solution combined with normal saline ir-rigation can decrease the superficial infection rate and deep infection rate effectively in the course of spinal surgery.