CAJ | 학술논문

目的：探讨急性心肌梗死 B 型钠尿肽(BNP)与左心功能及预后的相关性。方法：收治急性心肌梗死患者60例，依据血浆 BNP 水平分为对照组(BNP≤250 pg/mL)31例和研究组(BNP＞250 pg/mL)29例，比较两组的 Killip 分级与左室射血分数(LVEF)，并分析两组院内不良事件发生情况。结果：随着BNP水平的升高，两组的Killip分级构成中Ⅱ级以上的比例明显增加，而 LVEF 则逐渐下降，研究组 KillipⅡ级比例明显高于对照组，且 LVEF 低于对照组(P＜0.05)。结论：急性心肌梗死患者BNP水平和Killip分级的严重程度呈现正相关、和LVEF呈现负相关，与院内不良事件发生率无明显相关性。
목적：탐토급성심기경사 B 형납뇨태(BNP)여좌심공능급예후적상관성。방법：수치급성심기경사환자60례，의거혈장 BNP 수평분위대조조(BNP≤250 pg/mL)31례화연구조(BNP＞250 pg/mL)29례，비교량조적 Killip 분급여좌실사혈분수(LVEF)，병분석량조원내불량사건발생정황。결과：수착BNP수평적승고，량조적Killip분급구성중Ⅱ급이상적비례명현증가，이 LVEF 칙축점하강，연구조 KillipⅡ급비례명현고우대조조，차 LVEF 저우대조조(P＜0.05)。결론：급성심기경사환자BNP수평화Killip분급적엄중정도정현정상관、화LVEF정현부상관，여원내불량사건발생솔무명현상관성。
Objective:To explore the correlation of BNP in acute myocardial infarction with left ventricular function and prognosis. Methods:60 patients with acute myocardial infarction were selected.According to the level of plasma BNP,they were divided into the control group(BNP≤250 pg/mL) of 31 cases and the study group(BNP>250 pg/mL) of 29 cases.We compared the Killip classification and the left ventricular ejection fraction(LVEF),and analyzed the adverse events of the two groups.Results:With the elevation of BNP level,the proportion of Ⅱ grade and above in Killip classification of the two groups was significantly increased, and LVEF was going down.In the study group,the proportion of Ⅱ grade in Killip was significantly higher than the control group, and the LVEF was lower than that of the control group(P<0.05).Conclusion:In patients with acute myocardial infarction,the level of BNP was positively correlated with the severity of Killip grade.It was negatively correlated with LVEF,and there was no significant correlation with adverse events.