上海医药
上海醫藥
상해의약
SHANGHAI MEDICAL & PHARMACEUTICAL JOURNAL
2015年
16期
4-8
,共5页
结直肠癌%肝转移%多学科综合治疗
結直腸癌%肝轉移%多學科綜閤治療
결직장암%간전이%다학과종합치료
colorectal cancer%liver metastases%multi-disciplinary treatment
结直肠癌是消化道最常见的恶性肿瘤之一。肝脏是结直肠癌最主要的转移器官,仅有<20%的结直肠癌肝转移(colorectal liver metastasis,CRLM)能手术切除,肝转移是结直肠癌患者的重要致死原因之一。为此,国内外制定了很多关于CRLM的“诊治指南”和“规范”。由于我国各家医院的医疗水平参差不齐,难以完全按照这些“指南”和“规范”推荐的措施治疗CRLM。本文从手术切除、新辅助化疗和辅助化疗、局部治疗及多学科综合治疗等方面阐述适合CRLM首诊医师的治疗策略。
結直腸癌是消化道最常見的噁性腫瘤之一。肝髒是結直腸癌最主要的轉移器官,僅有<20%的結直腸癌肝轉移(colorectal liver metastasis,CRLM)能手術切除,肝轉移是結直腸癌患者的重要緻死原因之一。為此,國內外製定瞭很多關于CRLM的“診治指南”和“規範”。由于我國各傢醫院的醫療水平參差不齊,難以完全按照這些“指南”和“規範”推薦的措施治療CRLM。本文從手術切除、新輔助化療和輔助化療、跼部治療及多學科綜閤治療等方麵闡述適閤CRLM首診醫師的治療策略。
결직장암시소화도최상견적악성종류지일。간장시결직장암최주요적전이기관,부유<20%적결직장암간전이(colorectal liver metastasis,CRLM)능수술절제,간전이시결직장암환자적중요치사원인지일。위차,국내외제정료흔다관우CRLM적“진치지남”화“규범”。유우아국각가의원적의료수평삼차불제,난이완전안조저사“지남”화“규범”추천적조시치료CRLM。본문종수술절제、신보조화료화보조화료、국부치료급다학과종합치료등방면천술괄합CRLM수진의사적치료책략。
Colorectal cancer is one of the most common malignant tumors of digestive tract.The liver is a frequent site of metastatic colorectal disease. Only less than 20% of colorectal liver metastases (CRLM ) can be surgically resected, so that the liver metastases is one of the important causes of death in patients withCRLM. For this reason, a lot of the “guidelines for diagnosis and treatment” and “criterion” for CRLM were formulated at home and abroad. Because of the uneven medical levels in various hospitals of China, it is dififcult to completely follow the “guidelines” and “criterion” in treatment of CRLM. Therefore, this article summarizes therapeutic measures suitable for majority of doctors in treatment of CRLM including surgery, neoadjuvant chemotherapy and adjuvant chemotherapy, local treatment and multi-disciplinary treatment.