CAJ | 학술논문

背景：研究已证明膨体聚四氟乙烯人工血管具有良好的疏水性表面、抗水渗透性及生物耐久性。目的：观察膨体聚四氟乙烯人工血管移植修复创伤性四肢干动脉缺损的效果。方法：纳入38例创伤性四肢干动脉缺损患者，其中男30例，女8例，年龄17-61岁，予以常规补液、抗休克治疗、抗炎、清创处理后，均实施膨体聚四氟乙烯人工血管移植修复治疗。修复后随访12个月，了解患者修复后患肢恢复情况和血管通畅情况等。结果与结论：实施膨体聚四氟乙烯人工血管移植修复后，患者血管均全部通畅，未出现死亡和截肢病例，患肢均恢复正常血运，未发生血管吻合口感染，影像学检查显示血管通畅率达到100%。修复后随访12个月，血管内超声检查显示人工血管内壁均处于光滑状态，未出现明显附壁血栓、吻合口位狭窄现象，血管通畅率达到92%(35/38)，未发生与人工血管材料相关的不良反应。表明利用膨体聚四氟乙烯人工血管移植修复创伤性四肢干动脉缺损具有良好的表面抗凝血性能及长期通畅效果。
배경：연구이증명팽체취사불을희인공혈관구유량호적소수성표면、항수삼투성급생물내구성。목적：관찰팽체취사불을희인공혈관이식수복창상성사지간동맥결손적효과。방법：납입38례창상성사지간동맥결손환자，기중남30례，녀8례，년령17-61세，여이상규보액、항휴극치료、항염、청창처리후，균실시팽체취사불을희인공혈관이식수복치료。수복후수방12개월，료해환자수복후환지회복정황화혈관통창정황등。결과여결론：실시팽체취사불을희인공혈관이식수복후，환자혈관균전부통창，미출현사망화절지병례，환지균회복정상혈운，미발생혈관문합구감염，영상학검사현시혈관통창솔체도100%。수복후수방12개월，혈관내초성검사현시인공혈관내벽균처우광활상태，미출현명현부벽혈전、문합구위협착현상，혈관통창솔체도92%(35/38)，미발생여인공혈관재료상관적불량반응。표명이용팽체취사불을희인공혈관이식수복창상성사지간동맥결손구유량호적표면항응혈성능급장기통창효과。
BACKGROUND:Vascular grafts made of expanded polytetrafluoroethylene have been shown to have highly hydrophobic surface characterized by resistance to water penetration and biological durability. OBJECTIVE:To investigate the effects of vascular grafts made of expanded polytetrafluoroethylene for repair of peripheral arterial injuries. METHODS:Thirty-eight patients with peripheral arterial injuries, consisting of 30 males and 8 females, aged 17-61 years, were included in this study. After conventional fluid infusion, anti-shock treatment, anti-inflammation, and debridement, they received implantation of vascular grafts made of expanded polytetrafluoroethylene. A 12-month folow-up observation was performed to investigate the recovery of affected limbs and vascular patency in patients. RESULTS AND CONCLUSION:After implantation of vascular grafts made of expanded polytetrafluoroethylene, al vessels were unblocked and no cases died or had limbs amputated. Blood supply of al affected limbs recovered to normal and there was no vascular anastomotic infection. Imaging results showed that vascular patency rate was 100%. Ultrasound examination results showed that at the end of the folow-up period, the inner wal of the vascular grafts was smooth, obvious mural thrombus or anastomotic stenosis did not occur in any case, vascular patency rate was 92% (35/38), and no adverse reactions related to artificial vessels were observed. These findings suggest that vascular grafts made of expanded polytetrafluoroethylene for repair of peripheral arterial injuries exhibit striking surface anticoagulant property and long-term patency.