CAJ | 학술논문

利用常压低氧屋模拟2 500m高原急性缺氧,测试了6名世居平原的男子在常氧和急性缺氧情况下,中等强度运动前后中动脉经颅多普勒血流速度的变化.结果显示,急性缺氧暴露情况下,安静时平均脑血流速度(Vm)、收缩期血流速度(Vp)和舒张期血流速度(Vd)从第5 min到第20 min都持续上升,且Vd增加幅度最大.常氧和急性缺氧运动后即刻,Vm和Vp均显著增加,常氧运动后Vm、Vp的增加幅度均高于急性缺氧运动后;常氧运动后Vd增加,而急性缺氧运动后Vd略有降低.提示,急性缺氧主要通过调节脑血管阻力增加舒张期血流速度,从而增加脑血流量来满足动脉氧含量下降时大脑的供氧需求;急性缺氧运动与常氧运动一样,都是通过增加收缩期血流速度来满足大脑供氧需求,但急性缺氧暴露抑制了运动对脑血流速度的增加效应;与常氧运动、急性缺氧相比,急性缺氧运动对舒张期血流速度的影响比对平均脑血流速度和收缩期血流速度的影响要大.
이용상압저양옥모의2 500m고원급성결양,측시료6명세거평원적남자재상양화급성결양정황하,중등강도운동전후중동맥경로다보륵혈류속도적변화.결과현시,급성결양폭로정황하,안정시평균뇌혈류속도(Vm)、수축기혈류속도(Vp)화서장기혈류속도(Vd)종제5 min도제20 min도지속상승,차Vd증가폭도최대.상양화급성결양운동후즉각,Vm화Vp균현저증가,상양운동후Vm、Vp적증가폭도균고우급성결양운동후;상양운동후Vd증가,이급성결양운동후Vd략유강저.제시,급성결양주요통과조절뇌혈관조력증가서장기혈류속도,종이증가뇌혈류량래만족동맥양함량하강시대뇌적공양수구;급성결양운동여상양운동일양,도시통과증가수축기혈류속도래만족대뇌공양수구,단급성결양폭로억제료운동대뇌혈류속도적증가효응;여상양운동、급성결양상비,급성결양운동대서장기혈류속도적영향비대평균뇌혈류속도화수축기혈류속도적영향요대.
The velocity of middle cerebral blood flow of six sea level native males was measured before and after moderate constant exercise on normoxia and acute hypoxia using normobaric hypoxic house to simulate the acute hypoxia at altitude of 2 500m. The result showed that the rest mean velocity, peak velocity and End diastolic velocity rose continuously from the 5^th minute to 20^th minute on acute exposure and increment of peak velocity was the most. Mean velocity and peak velocity increased obviously instantly after exercise not only on normoxia but also on acute hypoxia. End diastolic velocity increased after exercise on normoxia but decreased slightly on acute hypoxia. It suggested that oxygen supply meeting the need for brain was mainly provided with the argument of cerebral flow through increasing of velocity of CBF. The need of oxygen supply for brain was provided by peak velocity of CBF in exercise on acute hypoxia and normoxia, Acute hypoxia restrained the effect of increasing of velocity CBF induced by exercise.