CAJ | 학술논문

选择年龄31～55岁的Ⅱ型糖尿病患者，38人为实验对象。同时选取同龄的健康男性22人作为对照，抽取静脉血进行CD4＋、CD8＋及sIL-2R检查。指导糖尿病患者进行12周的有氧运动，其中32人顺利完成运动后再次抽取静脉血进行CD4＋、CD8＋及血清sIL-2R检查。结果：与对照组相比运动前糖尿病患者CD4＋、CD8＋无明显改变，但CD4＋／CD8＋明显降低，血清sIL-2R值明显升高。12周有氧运动完成后，糖尿病患者CD4＋／CD8＋比值明显升高而血清SIL-2R值明显降低。结论：有氧运动可能通过提高CD4＋／CD8＋比值并降低血清sIL-2R水平来改善糖尿病患者的细胞免疫功能。
선택년령31～55세적Ⅱ형당뇨병환자，38인위실험대상。동시선취동령적건강남성22인작위대조，추취정맥혈진행CD4＋、CD8＋급sIL-2R검사。지도당뇨병환자진행12주적유양운동，기중32인순리완성운동후재차추취정맥혈진행CD4＋、CD8＋급혈청sIL-2R검사。결과：여대조조상비운동전당뇨병환자CD4＋、CD8＋무명현개변，단CD4＋／CD8＋명현강저，혈청sIL-2R치명현승고。12주유양운동완성후，당뇨병환자CD4＋／CD8＋비치명현승고이혈청SIL-2R치명현강저。결론：유양운동가능통과제고CD4＋／CD8＋비치병강저혈청sIL-2R수평래개선당뇨병환자적세포면역공능。
Methods： 38 subjects of 2 diabetes men aged 31 - 35 are assigned to 12 weeks of aerobic exercise training. 22 normal men of the same age are assigned as control group and draw blood to test CD4 ＋, CD8 ＋ and sIL -2R before and after instructing the patients to do 12 - week aerobic exercise training of 32 patients who complete the exercise. Results： Comparing with control group, the CD4 ＋ , CD8 ＋ of type 2 diabetes do not change obviously, but the CD4 ＋/CD8 ＋ ratios decreased and serum SIL- 2R decreased obviously. After 12 -week exercise training, the level of the plasma sIL-2R decreased and CD4 ＋/CD8 ＋ ratios increased in patients with type 2 diabetes. Conclusion： the aerobic exercise can improve the function of cell - mediated immunity of type 2 diabetes through decreasing the level of serum sIL- 2R and increasing CD4 ＋/CD8 ＋ ratios.