CAJ | 학술논문

目的：研究递增负荷运动对脑脊液（cerebrospinal fluid CSF）中单胺类神经递质动态变化的影响，为深入探讨运动性中枢神经疲劳机制提供基础研究资料。方法：29只SD雄性大鼠，随机分为对照组（C组，n=10）、递增负荷运动后即刻组（E1组，n=10）、递增负荷运动后24h组（E2组，n=9）。抽取大鼠CSF，用高效液相色谱-荧光检测法检测CSF中去甲肾上腺素（NE）、5-羟色胺（5-HT）的含量。结果：E1组中NE和5-HT含量较C组分别呈极显著性和显著性升高（P〈0．01、P〈0．05）；E2组中NE和5-HT含量较C组无差异性变化。结论：1．递增负荷运动后的即刻，CSF中NE和5-HT含量均升至最高，对降低运动性中枢疲劳有一定的意义。2．递增负荷运动后的24h，CSF中的NE和5-HT含量降低为脑组织提供了良好的微环境。
목적：연구체증부하운동대뇌척액（cerebrospinal fluid CSF）중단알류신경체질동태변화적영향，위심입탐토운동성중추신경피로궤제제공기출연구자료。방법：29지SD웅성대서，수궤분위대조조（C조，n=10）、체증부하운동후즉각조（E1조，n=10）、체증부하운동후24h조（E2조，n=9）。추취대서CSF，용고효액상색보-형광검측법검측CSF중거갑신상선소（NE）、5-간색알（5-HT）적함량。결과：E1조중NE화5-HT함량교C조분별정겁현저성화현저성승고（P〈0．01、P〈0．05）；E2조중NE화5-HT함량교C조무차이성변화。결론：1．체증부하운동후적즉각，CSF중NE화5-HT함량균승지최고，대강저운동성중추피로유일정적의의。2．체증부하운동후적24h，CSF중적NE화5-HT함량강저위뇌조직제공료량호적미배경。
Objective ： To research the impact of additive loading exercises on the dynamic change in CSF to provide basic research materials for sports -induced central nerve fatigue mechanism. Methods： 29 SD male rats are randomly divided into the control group, （Group C n =10） the immediate group after additive exercises （Group E1 n = 10） and 24h group after additive exercises （ Group E2 n = 10）. Rats＇CSF is extracted to test the content of NE and 5 - HT. Results： There is a marked increase in the NE and 5 -HT content in group E1 compared with that in group C （P 〈0.01 P 〈 0.05 ; there is no marked difference in the NE and 5 - HT content in group E2 and that in group C. Conclusion ： After the additive loading exercises, the NE and 5 - HT content in the CSF in the immediate group rises to the highest level, which is of certain significance in decreasing sports - induced central nerve fatigue ; in the 24h group after the additive exercises, the NE and 5 - HT content in CSF are lowered to produce a good micro environment for the cerebral tissue.