天津体育学院学报
天津體育學院學報
천진체육학원학보
Journal of Tianjin Institute of Physical Education
2009年
1期
75~78
,共null页
运动 心理应激 海马 脑源性神经营养因子
運動 心理應激 海馬 腦源性神經營養因子
운동 심리응격 해마 뇌원성신경영양인자
exercise; mental stress; hippocampus; BDNF
目的：探讨适宜运动训练对心理应激大鼠海马脑源性神经营养因子（BDNF）水平的影响。方法：对sD大鼠进行为期8周，每次60min的游泳运动训练，并在运动后期施加2周的心理应激，测定大鼠海马CA1区脑源性神经营养因子（BDNF）积分光密度、平均光密度、阳性物面积，面密度、阳性细胞数、数密度水平变化。结果：（1）经过2周心理应激后，心理应激组大鼠海马CA1区脑源性神经营养因子（BDNF）积分光密度、平均光密度、阳性物面积，面密度、阳性细胞数、数密度水平显著低于对照组；（2）经过8周运动训练后，运动组大鼠海马CA1区脑源性神经营养因子（BDNF）积分光密度、平均光密度、阳性物面积，面密度、阳性细胞数、数密度水平显著高于对照组；同时运动＋心理应激组大鼠海马CA1区脑源性神经营养因子（BDNF）积分光密度、平均光密度、阳性物面积，面密度、阳性细胞数、数密度水平显著高于应激组；结论：适宜运动训练可以降低心理应激反应程度，使大脑海马区BDNF水平提高，维持大脑海马区在应激状态下的生理功能稳定。
目的：探討適宜運動訓練對心理應激大鼠海馬腦源性神經營養因子（BDNF）水平的影響。方法：對sD大鼠進行為期8週，每次60min的遊泳運動訓練，併在運動後期施加2週的心理應激，測定大鼠海馬CA1區腦源性神經營養因子（BDNF）積分光密度、平均光密度、暘性物麵積，麵密度、暘性細胞數、數密度水平變化。結果：（1）經過2週心理應激後，心理應激組大鼠海馬CA1區腦源性神經營養因子（BDNF）積分光密度、平均光密度、暘性物麵積，麵密度、暘性細胞數、數密度水平顯著低于對照組；（2）經過8週運動訓練後，運動組大鼠海馬CA1區腦源性神經營養因子（BDNF）積分光密度、平均光密度、暘性物麵積，麵密度、暘性細胞數、數密度水平顯著高于對照組；同時運動＋心理應激組大鼠海馬CA1區腦源性神經營養因子（BDNF）積分光密度、平均光密度、暘性物麵積，麵密度、暘性細胞數、數密度水平顯著高于應激組；結論：適宜運動訓練可以降低心理應激反應程度，使大腦海馬區BDNF水平提高，維持大腦海馬區在應激狀態下的生理功能穩定。
목적：탐토괄의운동훈련대심리응격대서해마뇌원성신경영양인자（BDNF）수평적영향。방법：대sD대서진행위기8주，매차60min적유영운동훈련，병재운동후기시가2주적심리응격，측정대서해마CA1구뇌원성신경영양인자（BDNF）적분광밀도、평균광밀도、양성물면적，면밀도、양성세포수、수밀도수평변화。결과：（1）경과2주심리응격후，심리응격조대서해마CA1구뇌원성신경영양인자（BDNF）적분광밀도、평균광밀도、양성물면적，면밀도、양성세포수、수밀도수평현저저우대조조；（2）경과8주운동훈련후，운동조대서해마CA1구뇌원성신경영양인자（BDNF）적분광밀도、평균광밀도、양성물면적，면밀도、양성세포수、수밀도수평현저고우대조조；동시운동＋심리응격조대서해마CA1구뇌원성신경영양인자（BDNF）적분광밀도、평균광밀도、양성물면적，면밀도、양성세포수、수밀도수평현저고우응격조；결론：괄의운동훈련가이강저심리응격반응정도，사대뇌해마구BDNF수평제고，유지대뇌해마구재응격상태하적생리공능은정。
Objective： To explore the effect of exercise training on concentration of hippocampus brain-derived neurotrophic factor （BDNF） in mental stress rats. Methods： SD rats were conducted on exercise training with 60 min swimming for 8 weeks and exerted on mental stress for 2 weeks in the later stage of training. Concentration of points of optical density, average optical density, positive substance acreage, acreage density, positive cell, number density of BD- NF in hippocampus CA1 area were measured. Results： First, after 2 weeks mental stress, points of optical density, average optical density, positive substance acreage, acreage density, positive cell, number density of BDNF in hippocampus CA1 area was significant lower than that in control group. Second, after 8 weeks training, points of optical density, average optical density, positive substance acreage, acreage density, positive cell, number density of BDNF in hippocampus CA1 area were significant higher than that in control group, points of optical density, average optical density, positive substance acreage, acreage density, positive cell, number density of BDNF in hippocampus CA1 area training plus mental stress were higher than that in mental stress group. Conclusion： Adapted training can decrease the intensity of mental stress and increase BDNF in hippocampus, and maintain the stabilization of brain function under mental stress state.
