CAJ | 학술논문

人类ACTN3基因的多态性导致约10亿人缺乏ACTN3蛋白。ACTN3缺失并不导致肌肉疾病，提示ACTN3对于肌肉的功能并不是关键性的。ACTN2也许代偿了ACTN3的功能。但作为快肌纤维Z线的结构成分，ACTN3的存在可能有利于人类速度力量型运动技能的发展，ACTN3RR基因型运动员的肌肉内Ⅱ型快肌纤维多于XX基因型，对运动训练的反应性也强些。因此认为ACTN3是一个与肌肉爆发力有关的基因，它也许可以用于选拔优秀的速度或力量型运动员。但ACTN3缺乏是否给耐力型运动员带来好处还有待进一步研究。
인류ACTN3기인적다태성도치약10억인결핍ACTN3단백。ACTN3결실병불도치기육질병，제시ACTN3대우기육적공능병불시관건성적。ACTN2야허대상료ACTN3적공능。단작위쾌기섬유Z선적결구성분，ACTN3적존재가능유리우인류속도역량형운동기능적발전，ACTN3RR기인형운동원적기육내Ⅱ형쾌기섬유다우XX기인형，대운동훈련적반응성야강사。인차인위ACTN3시일개여기육폭발력유관적기인，타야허가이용우선발우수적속도혹역량형운동원。단ACTN3결핍시부급내력형운동원대래호처환유대진일보연구。
Human ACTN3 gene polymorphism results in lack of ACTN3 protein among about 10 billion people. Lack of ACTN3 wont result in muscle diseases, which indicates that ACTN3 is not key to muscle functions. ACTN2 may replace the function of ACTN3 but the latter may contribute to the development of sports skills which calls for speed and strength. ACTN3 is a gene responsible for muscle eruptive force and may be used to select talent players with speed and strength, but further research should be done to determine whether lack of ACTN3 will be beneficial to athletes with stamina.