CAJ | 학술논문

快感缺失，指的是体验快乐的能力下降，广泛出现在抑郁症中，但同时也是其他如精神分裂症的重要症状。虽然快感缺失在精神病理学上非常重要，但较少受到研究重视。文章探讨了抑郁症和快感缺失的关系以及快感缺失个体的大脑奖励系统受损的神经机制，同时介绍了快感缺失可以进一步区分为期待性和消费性两种损害类型以及研究所用的主客观测量方法。指出快感缺失作为抑郁症最有可能的内表现型及其对疾病发展的作用，需要进一步研究深入。
쾌감결실，지적시체험쾌악적능력하강，엄범출현재억욱증중，단동시야시기타여정신분렬증적중요증상。수연쾌감결실재정신병이학상비상중요，단교소수도연구중시。문장탐토료억욱증화쾌감결실적관계이급쾌감결실개체적대뇌장려계통수손적신경궤제，동시개소료쾌감결실가이진일보구분위기대성화소비성량충손해류형이급연구소용적주객관측량방법。지출쾌감결실작위억욱증최유가능적내표현형급기대질병발전적작용，수요진일보연구심입。
Anhedonia is defined as the diminished capacity to experience pleasure, which is widely recognized to occur in depression, and is a prominent feature that is involved in several types of psychiatric disorders and maladaptive behaviors. Although anhedonia is regarded as an important symptom in psychopathology, it has received relatively little attention. To better understand the role of anhedonia in depression, this paper reviews the relationship between depression and anhedonia, and the neural substrates of anhedonia linked to a dysfunction of the dopaminergic reward system. It also highlights two facets of hedonic capacity （anticipatory and consummatory pleasure） and addresses some measurement issues of anhedonia. Further research is needed to be conducted in the near future to explore whether anhedonia might be the most possible endophenotype of depression and the role in development of depression.