CAJ | 학술논문

抑郁症患者负性认知加工偏向是导致抑郁的一个主要认知因素，是抑郁症的一个稳定特质。这种偏向与对负性情绪刺激自下而上的情绪加工增强有关，表现为杏仁核和梭状回等脑区过度激活；也与自上而下的认知控制功能不足有关，表现为背外侧前额皮质、前扣带回等脑区活性不足。文章在前人研究基础上，提出了关于抑郁症情绪加工与认知控制脑机制的一个理论假说，即抑郁症的产生是由于抑郁症患者情绪加工脑区过度激活与认知控制脑区功能降低之间的相互作用而形成的恶性循环所介导。目前证明此理论假说在研究内容、研究材料、研究技术等方面还存在一些问题，这些可能是未来研究的方向。
억욱증환자부성인지가공편향시도치억욱적일개주요인지인소，시억욱증적일개은정특질。저충편향여대부성정서자격자하이상적정서가공증강유관，표현위행인핵화사상회등뇌구과도격활；야여자상이하적인지공제공능불족유관，표현위배외측전액피질、전구대회등뇌구활성불족。문장재전인연구기출상，제출료관우억욱증정서가공여인지공제뇌궤제적일개이론가설，즉억욱증적산생시유우억욱증환자정서가공뇌구과도격활여인지공제뇌구공능강저지간적상호작용이형성적악성순배소개도。목전증명차이론가설재연구내용、연구재료、연구기술등방면환존재일사문제，저사가능시미래연구적방향。
Depression is characterized by a negativity bias which is a stable factor of it. The bias reflects enhanced bottom-up responses to affective stimuli, linked to deficits in amygdala and fusiform gyrus function. Alternatively, the bias also reflects impaired top-down cognitive control, linked to deficits in dorsolateral prefrontal cortex and anterior cingulate function. A new hypothesis that the occurrence of depression is caused by interaction of increased activity in affecfive brain regions and deficits in cognitive-control brain regions was brought forward. To prove the hypothesis, there are still some important questions to be answered, which might be the direction of future studies.