CAJ | 학술논문

探讨了运动对高脂饮食诱导的肥胖Wistar大鼠胰岛素敏感性和甘油三酯脂酶mRNA、脂联素mRNA表达的影响。随机将大鼠分为3组：高脂饮食喂养加运动组（简称运动组）、高脂饮食喂养组（简称高脂组）和标准饮食对照组（简称对照组）。以RT-PGR法半定量测定脂肪组织部分甘油三酯脂酶mRNA、脂联素mRNA的表达同时检测血游离脂肪酸（FFA）、甘油三酯（TG）,并用稳态模式评估法（HOMA）评价胰岛素抵抗（IR）指数,实验结果显示,有氧运动具有改善高脂饮食诱导的脂质异常、提高胰岛素敏感性以及调节脂肪因子表达的作用。
탐토료운동대고지음식유도적비반Wistar대서이도소민감성화감유삼지지매mRNA、지련소mRNA표체적영향。수궤장대서분위3조：고지음식위양가운동조（간칭운동조）、고지음식위양조（간칭고지조）화표준음식대조조（간칭대조조）。이RT-PGR법반정량측정지방조직부분감유삼지지매mRNA、지련소mRNA적표체동시검측혈유리지방산（FFA）、감유삼지（TG）,병용은태모식평고법（HOMA）평개이도소저항（IR）지수,실험결과현시,유양운동구유개선고지음식유도적지질이상、제고이도소민감성이급조절지방인자표체적작용。
This article has explored the effect of aerobic exercise on the insulin sensitivity,adipokines expression mRNA and adiponectin mRNA in high-fat diet fed Wistar rats.Rats were randomized into three groups： aerobic exercise group,fed with high fat diet group,and control group.The lipid adipokines expression mRNA and adiponectin mRNA and the free fatty acid（FFA）,triglycerid（TG） were detected by semi-quantity RT-PGR.Homeostasis model assessment was used to evaluate the insulin resistance（IR） index.The result indicates that aerobic exercise may reverse high-fat diet induced lipid abnormalities,improve insulin sensitivity,and regulate the expression of adiponectin＇s mRNA.