CAJ | 학술논문

通过雌性大鼠去卵巢模型来模拟女性绝经后的状态，比较研究跳跃和游泳两种不同方式运动对去卵巢大鼠骨的影响，以期为骨质疏松的预防发现更为有效的运动模式。将32只3月龄SD雌性大鼠随机分为4组：假手术组、安静组、游泳组和跳跃组。其中安静组、游泳组和跳跃组行卵巢摘除手术，假手术组只行假手术（即不摘除卵巢）。8周后，测定各组大鼠体重、骨密度（BMD）、骨生物力学和骨代谢相关指标。结果发现：与安静组比较，跳跃组大鼠股骨BMD、最大载荷、弹性载荷、破坏栽荷、能量吸收和弹性应力均显著性升高；跳跃组大鼠血清Ca和抗酒石酸酸性磷酸酶（STR—ACP）水平显著性降低。与安静组比较，游泳纽大鼠除了血清Ca水平显著性降低外（P〈0．05），其他指标虽有变化趋势，但变化不显著。结果说明：8周跳跃运动对去卵巢大鼠股骨BMD、骨生物力学以及骨代谢生化指标均起到较明显的改善作用。而8周游泳运动对去卵巢大鼠股骨BMD、骨生物力学以及骨代谢生化指标的改善效果不如跳跃运动。跳跃运动与游泳相比，在改善骨代谢，促进骨健康方面的作用更加明显，提示能更有利于预防绝经后女性出现骨质疏松。
통과자성대서거란소모형래모의녀성절경후적상태，비교연구도약화유영량충불동방식운동대거란소대서골적영향，이기위골질소송적예방발현경위유효적운동모식。장32지3월령SD자성대서수궤분위4조：가수술조、안정조、유영조화도약조。기중안정조、유영조화도약조행란소적제수술，가수술조지행가수술（즉불적제란소）。8주후，측정각조대서체중、골밀도（BMD）、골생물역학화골대사상관지표。결과발현：여안정조비교，도약조대서고골BMD、최대재하、탄성재하、파배재하、능량흡수화탄성응력균현저성승고；도약조대서혈청Ca화항주석산산성린산매（STR—ACP）수평현저성강저。여안정조비교，유영뉴대서제료혈청Ca수평현저성강저외（P〈0．05），기타지표수유변화추세，단변화불현저。결과설명：8주도약운동대거란소대서고골BMD、골생물역학이급골대사생화지표균기도교명현적개선작용。이8주유영운동대거란소대서고골BMD、골생물역학이급골대사생화지표적개선효과불여도약운동。도약운동여유영상비，재개선골대사，촉진골건강방면적작용경가명현，제시능경유리우예방절경후녀성출현골질소송。
By using a model of female rat ovariectomy to simulate women＇s postmenopausal state, the authors compared and studied the effects of such two different ways of exercising as jumping and swimming on the bones of ovariectomized rats, hoping to find a more effective mode of exercising for preventing osteoporosis. The authors divided 30 3 months old female SD rats randomly into 4 groups： a sham operated group, a calm group, a swimming group and a jumping group, in which the calm group, swimming group and jumping group were operated for ova- riectomy, while the sham operated group was just subjected to a sham operation （i.e. no ovariectomy）. 8 weeks later, the weight, bone mineral density （BMD）, bone biomechanics and bone metabolism related indexes of the rats in various groups were measured. The author revealed the following findings： as compared with the calm group, the BMD, maximum load, elastic load, destructive load, energy absorption and elastic stress of the femur of the rats in the jumping group increased significantly; the levels of blood serum Ca and tartrate-resistant acid phosphatase （STR-ACP） of the rats in the jumping group decreased significantly; as compared with the calm group, except that the blood serum Ca level of the rats in the swimming group decreased significantly （P〈0.05）, all the other indexes changed insignificantly although they shown a trend of changing. The said findings indicated the followings： the 8-week jumping exercise played a role in significantly improving the BMD, bone biomechanical and bone meta- bolic biochemical indexes of ovariectomized rats, while the results of improvement of the BMD, bone biomechani- cal and bone metabolic biochemical indexes of ovariectomized rats, produced by the 8-week swimming exercise were not as good as those produced by the jumping exercise; as compared with swimming, the jumping exercise played a more significant role in improving metabolism and promoting bone health, which suggests that it is more conducive to preventing osteoporosis from occurring to postmenopausal women.