CAJ | 학술논문

目的评价窄谱紫外线联合0.05%卡泊三醇治疗寻常性斑块状银屑病的疗效和安全性。方法对35例轻、中度寻常性斑块状银屑病患者采用窄谱紫外线每周3次照射,联合0.005%卡泊三醇每天2次外用,共治疗8周,用PASI积分评价疗效。结果治疗开始2周后出现疗效,随着治疗时间的延长,有效率逐渐提高,治疗结束时痊愈率达到40%,有效率达85.71%,4例发生皮肤刺激反应,占11.43%。结论窄谱紫外线联合0.05%卡泊三醇治疗寻常性斑块状银屑病具有起效快、疗效好、副作用小的优点。
목적평개착보자외선연합0.05%잡박삼순치료심상성반괴상은설병적료효화안전성。방법대35례경、중도심상성반괴상은설병환자채용착보자외선매주3차조사,연합0.005%잡박삼순매천2차외용,공치료8주,용PASI적분평개료효。결과치료개시2주후출현료효,수착치료시간적연장,유효솔축점제고,치료결속시전유솔체도40%,유효솔체85.71%,4례발생피부자격반응,점11.43%。결론착보자외선연합0.05%잡박삼순치료심상성반괴상은설병구유기효쾌、료효호、부작용소적우점。
Objective：To evaluate the curative effect and safety of the narrow-band ultraviolet with 0.05% calcipotriol in the treatment of plaque psoriasis vulgaris.Methods：35 patients with the mild to moderate plaque psoriasis vulgaris were treated for 8 weeks with narrow-spectrum ultraviolet radiation three times a week,coupled with 0.005% calcipotriol twice daily topical,and assessed by the PASI evaluation points.Results：The curative effect of the treatment occurs two weeks later and increases over time.The treatment concludes with the cure rate of 40%,effective rate of 85.71%,and 4 cases of skin irritation accounting for 11.43%.Conclusion：Narrow-band ultraviolet 0.05% calcipotriol with plaque psoriasis vulgaris has the advantages of the rapid and satisfactory effect and little side effect.