CAJ | 학술논문

目的研制基于SolutolHS纳米乳体系,并对其理化性质作出初步评价。方法采用滴加水法制备纳米乳,考察纳米乳的粘度、pH值、粒径、粒径分布、ξ电位、电导率和稳定性。结果制备出SolutolHS纳米乳体系粒径均在20~30nm之间,性质稳定。结论 SolutolHS纳米乳体系性质优良,含表面活性剂少,可用于疏水性药物的载体。
목적연제기우SolutolHS납미유체계,병대기이화성질작출초보평개。방법채용적가수법제비납미유,고찰납미유적점도、pH치、립경、립경분포、ξ전위、전도솔화은정성。결과제비출SolutolHS납미유체계립경균재20~30nm지간,성질은정。결론 SolutolHS납미유체계성질우량,함표면활성제소,가용우소수성약물적재체。
Objective： To prepare SolutolHS-based microemulsion system and preliminary investigate their physical and chemical properties.Methods： nanoemulsion were prepared using titration method and characterized for viscosity,pH,globule size,size distributions,zeta potential,Conductivity and stability.Results：SolutolHS nanoemulsion system particle size in the range of 20-30 nm and very stable.Conclusion：SolutolHS The nanoemulsion system has good nature and containing small surfactants can be used for the carrier of hydrophobic drugs.