CAJ | 학술논문

近年研究表明,运动对抑郁有积极作用,其效果可媲关心理干预或药物治疗,甚至更为显著.而且适当运动无任何副作用,还能降低心血管疾病、糖尿病等的发病率.虽然运动作为抗抑郁的干预手段已引起了广泛关注,但其内在机制尚不明确.基于现有的抑郁症发病机理的各种假说,并结合运动抗抑郁的实证研究,提出运动抗抑郁的神经生物学机制可能涉及到中枢单胺类神经递质系统、神经营养物质、神经内分泌系统、神经免疫系统,以及中枢神经系统组织形态结构等方面的变化.这不仅进一步丰富运动抗抑郁机制的理论构架,而且为本领域的未来研究提供新视角.
근년연구표명,운동대억욱유적겁작용,기효과가비관심리간예혹약물치료,심지경위현저.이차괄당운동무임하부작용,환능강저심혈관질병、당뇨병등적발병솔.수연운동작위항억욱적간예수단이인기료엄범관주,단기내재궤제상불명학.기우현유적억욱증발병궤리적각충가설,병결합운동항억욱적실증연구,제출운동항억욱적신경생물학궤제가능섭급도중추단알류신경체질계통、신경영양물질、신경내분비계통、신경면역계통,이급중추신경계통조직형태결구등방면적변화.저불부진일보봉부운동항억욱궤제적이론구가,이차위본영역적미래연구제공신시각.
Researches in recent years show that physical exercise, as a non--pharmacological coping strategy, has been considered as effective as psychotherapy and even more effective than other pharmacological interventions with major depression. In addition,moderate exercise can reduce the incidence of cardiovascular disease and diabetes without any side effects. Effects of exercise in depression have attracted broad attention, yet the underlying mechanism is still unclear. Based on the pathological hypothesis on depres- sion, in combination with the empirical studies, the following factors are considered to explain the neurobi- ological effects of exercise in depression： central neurotransmitter, neurotrophic substance, neuroendocrine system,neuroimmune system,and morphological changes in central nervous system. It is supposed to enrich theoretical building and provide new perspectives for antidepressant effects of exercise.