CAJ | 학술논문

目的：探讨太极拳改善老年人原发性高血压的气体信号分子调控机制.方法：选取50名老年原发性高血压患者,随机分为高血压组、太极拳高压组,并选取25名健康老年志愿者作为对照组.其中太极拳高血压组进行12周太极拳练习,每次1h,每天1次,每周5天,分别在12周太极拳练习开始前1天和结束后次日清晨08：00～09：00,测试各组受试者SBP、DBP、NO和H2S.结果：太极拳练习能显著降低老年原发性高血压患者SBP、DBP,提高血清NO和H2S水平,且NO与SBP、DBP,H2S与SBP、DBP间均分别呈现显著负相关,NO与H2S间呈现显著正相关.结论：太极拳运动可多途径提高原发性高血压患者血清NO和H2S水平,改善原发性高血压患者的健康,提示内源性NO和H2S水平改善可能是太极拳降压效应的分子生物学机制之一.
목적：탐토태겁권개선노년인원발성고혈압적기체신호분자조공궤제.방법：선취50명노년원발성고혈압환자,수궤분위고혈압조、태겁권고압조,병선취25명건강노년지원자작위대조조.기중태겁권고혈압조진행12주태겁권연습,매차1h,매천1차,매주5천,분별재12주태겁권연습개시전1천화결속후차일청신08：00～09：00,측시각조수시자SBP、DBP、NO화H2S.결과：태겁권연습능현저강저노년원발성고혈압환자SBP、DBP,제고혈청NO화H2S수평,차NO여SBP、DBP,H2S여SBP、DBP간균분별정현현저부상관,NO여H2S간정현현저정상관.결론：태겁권운동가다도경제고원발성고혈압환자혈청NO화H2S수평,개선원발성고혈압환자적건강,제시내원성NO화H2S수평개선가능시태겁권강압효응적분자생물학궤제지일.
The purpose of this sludy was to explore the gaseous signal molecular mechanism that Taijiquan＇s intervention in aged essential hypertension. 50 subjects were randomly selected and divided into hypertension group and Taijiquan group. Meanwhile, 25 healthy aged volunteers were selected as control group. Taijiquan group exercised one hour per day, five days per week for 12 months. The indexes of SBP, DBP, NO and H2S of three groups were tested respectively before and after exercising Taijiquan. For the aged patients with essential hypertension, the SBP and DBP could be greatly reduced and the NO and H2S could be significantly improved by exercising Tai Ji Quan. There was negative correlation respectively between NO, H2S and SBP, DBP and positive correlation between NO and H2S. For the aged patients with essential hypertension, the level of plasma NO and H2S could be improved through many ways and the health could be promoted by exercising Taijiquan. It was suggested that improving the level of endogenous NO and H2S might be one of the molecular mechanisms that Taijiquans intervention in aged essential hypertension.