CAJ | 학술논문

随着“全球老龄化”时代的到来，老年人认知功能的下降引起了研究人员的广泛关注，其中年老化对决策的影响成为了近年来的一个新关注点。风险决策和模糊决策受生理性老化和病理性老化影响的研究显示，正常老化个体模糊决策能力受损，但其风险决策能力受老化影响较小；而病理性老化个体，以阿尔兹海默症患者为例，在两类决策行为上均表现出损伤；此外，脑神经机制的研究发现在完成决策任务时正常年老化个体纹状体激活模式与年轻人存在显著差异，病理性老化个体杏仁核与腹内侧前额叶的功能连接亦存在异常。未来的研究应同时考察并比较两类决策类型，结合外周和中枢神经证据，深入探讨老化对决策行为及神经环路造成影响的机制。
수착“전구노령화”시대적도래，노년인인지공능적하강인기료연구인원적엄범관주，기중년노화대결책적영향성위료근년래적일개신관주점。풍험결책화모호결책수생이성노화화병이성노화영향적연구현시，정상노화개체모호결책능력수손，단기풍험결책능력수노화영향교소；이병이성노화개체，이아이자해묵증환자위례，재량류결책행위상균표현출손상；차외，뇌신경궤제적연구발현재완성결책임무시정상년노화개체문상체격활모식여년경인존재현저차이，병이성노화개체행인핵여복내측전액협적공능련접역존재이상。미래적연구응동시고찰병비교량류결책류형，결합외주화중추신경증거，심입탐토노화대결책행위급신경배로조성영향적궤제。
The world is aging at its fastest rate ever. There are raising concerns on older adults＇ cognitive declining. The effects of aging on decision-making becomes one new focus recent years. Recent studies on decision-making from the aspects of physiological aging, pathological aging and its brain mechanisms showed that normal aging demonstrated impaired decision-making under ambiguity but intact decision-making under risk, whereas the pathological aging individuals, like Alzheimer＇s disease patients, demonstrated impairment of both kinds of decision-making on behaviors and brain functions. Future research needs to use multiple measures of decision-making in the same study and to combine both peripheral and central measures to investigate the aging effect on the behavior and neuro-circuits of decision-making.