CAJ | 학술논문

目的：通过实验研究探讨抗阻训练对老龄大鼠腓肠肌Ca2＋及线粒体膜电位的影响.方法：研究对象为雄性SD大鼠,人工喂养18月龄进行8周抗阻训练干预,分别以无负重、30％、50％、70％最大负重进行训练,跑台放置坡度为35°,跑速15m/ min,隔天抗阻训练.8周末检测腓肠肌胞浆Ca2＋及线粒体膜电位,并与安静组比较.结果：30％、50％最大负重抗阻训练两组老龄大鼠腓肠肌Ca2＋下降具有显著性意义（P＜0.05）;无负重、30％、50％最大负重抗阻训练三组老龄大鼠线粒体膜电位下降有极显著性差异（P＜0.01）.结论：低、中等负重抗阻训练能降低衰老过程中腓肠肌胞浆Ca2＋、提高线粒体膜电位,改善线粒体功能,从而预防、延迟衰老过程中线粒体功能障碍的发生.
목적：통과실험연구탐토항조훈련대노령대서비장기Ca2＋급선립체막전위적영향.방법：연구대상위웅성SD대서,인공위양18월령진행8주항조훈련간예,분별이무부중、30％、50％、70％최대부중진행훈련,포태방치파도위35°,포속15m/ min,격천항조훈련.8주말검측비장기포장Ca2＋급선립체막전위,병여안정조비교.결과：30％、50％최대부중항조훈련량조노령대서비장기Ca2＋하강구유현저성의의（P＜0.05）;무부중、30％、50％최대부중항조훈련삼조노령대서선립체막전위하강유겁현저성차이（P＜0.01）.결론：저、중등부중항조훈련능강저쇠로과정중비장기포장Ca2＋、제고선립체막전위,개선선립체공능,종이예방、연지쇠로과정중선립체공능장애적발생.
Objective： To study the effects of resistance training on the aging rats＇ gastrocnemius of Ca2＋ and mitochondrial membrane potential（mt）. Method： The male SD rats as the research object, after feeding 18 months, they were assigned as 0% , 30% , 50% , 70% maximum weight resistance training intervention. Ca2~ and mitochondrial membrane potential of gastrocnemius the aging process in the occurrence of mitochondrial dysfunctionwere tested after a period of quote of the day for 8 weeks treadmill training with the speed of 15m/min, slope as 35 o. Results： Compared with the aging control group, the gastrocnemius levels of Ca2＋ decreased and A~mt increased in the resistance training groups, among them with 30% , 50% maximum weight resistance training groups Ca2＋ decreased significantly （ P 〈 0.05, ）, and their mt increased extremely significance in 0%, 30%, 50% maximum weight resistance training groups （P 〈 0.01 ）. Conclusion： Low and moderate weight resistance training may be reduce Ca2＋ in gastrocnemius cytosolie,increased mitochondrial membrane potential, improve mitochondrial function, thereby, preventing and delaying the occurrence of mitochondrial dysfunction in the aging process.