CAJ | 학술논문

目的：观察药物结合乒乓球运动对老年性痴呆（AD）患者的影响。方法：将100例AD患者随机分为观察组和对照组，对照组患者给予叶酸10mg，维生素B12500μg，每日1次。观察组患者在对照组治疗基础上每隔1日增加1小时乒乓球运动。1年后对所有患者进行简易智力状态量表（MMSE）和日常生活活动能力量表（ADL）测定，同时检测患者尿中甲醛和神经丝蛋白（AD7c—NTP）的含量。结果：与对照组比较，治疗后观察组整体疗效明显优于对照组（P〈0．05）；MMSE评分有显著性差异（P〈0．05）；尿中甲醛和AD7c—NTP含量差异有统计学意义（P〈0．05）。结论：在补充叶酸、维生素B12的基础上结合乒乓球运动对AD患者的防治及生活自理能力有明显改善。
목적：관찰약물결합핑퐁구운동대노년성치태（AD）환자적영향。방법：장100례AD환자수궤분위관찰조화대조조，대조조환자급여협산10mg，유생소B12500μg，매일1차。관찰조환자재대조조치료기출상매격1일증가1소시핑퐁구운동。1년후대소유환자진행간역지력상태량표（MMSE）화일상생활활동능역량표（ADL）측정，동시검측환자뇨중갑철화신경사단백（AD7c—NTP）적함량。결과：여대조조비교，치료후관찰조정체료효명현우우대조조（P〈0．05）；MMSE평분유현저성차이（P〈0．05）；뇨중갑철화AD7c—NTP함량차이유통계학의의（P〈0．05）。결론：재보충협산、유생소B12적기출상결합핑퐁구운동대AD환자적방치급생활자리능력유명현개선。
Objective： To observe the effect of medicine in combination with table tennis on Alzheimer＇ s Disease （AD） patients. Methods： 100 cases of AD patients were randomly divided into observation group and control group, the control group played table tennis up to 1 hour were treated with folio acid and vitamin 10mg, B12 500μg, once a day. Patients in the observation group based on the treatment in control group every other day. After 1 year for all patients with Mini Mental State Scale （MMSE） and activities of daily living scale （ADL） were measured at the same time, detection of formaldehyde and neurofilament protein （ AD7c - NTP） in urine of patients with content. Results ： Compared with the control group, after treatment, the overall effect of observation group was superior to that of control group （ P 〈 0. 05 ） ; MMSE score had significant difference （P 〈 0.05 ） ; there was significant difference of formaldehyde and AD7c - NTP content in urine （ P 〈0. 05）. Conclusion： On the basis of folio acid, vitamin B12 combined with prevention with table tennis, self - care ability of seniles with AD is improved obviously.