CAJ | 학술논문

神经内分泌调节紊乱、宏量和微量营养素缺乏、体内代谢改变、慢性感染病灶的中毒（如果有的话）都可因繁重的心身负荷而导致免疫抵抗力降低；然而，这个问题尚未得到充分的研究，细节上仍呈碎片化。例如，细胞因子对负荷的反应仍不清楚，且细胞凋亡的部分过程和免疫系统紊乱形成的其他重要机制也仍不明确；然而对有关这些机制的了解能够促使运动员在大量负荷时期发展出适宜的和更多的生理途径以预防免疫系统紊乱和免疫缺陷。本研究的目的是探查以冬季2项为例的精英运动员免疫系统紊乱的机制。在这项研究中，考虑到专业化和数量是主要的战斗影响因素，作者使用了2种类型的负荷成分。冬季2项精英运动员复杂的免疫状态动态研究揭示了在训练和对抗活动中运动员免疫特性在大环上的变化，而其性质和严重程度取决于训练的时间。
신경내분비조절문란、굉량화미량영양소결핍、체내대사개변、만성감염병조적중독（여과유적화）도가인번중적심신부하이도치면역저항력강저；연이，저개문제상미득도충분적연구，세절상잉정쇄편화。례여，세포인자대부하적반응잉불청초，차세포조망적부분과정화면역계통문란형성적기타중요궤제야잉불명학；연이대유관저사궤제적료해능구촉사운동원재대량부하시기발전출괄의적화경다적생리도경이예방면역계통문란화면역결함。본연구적목적시탐사이동계2항위례적정영운동원면역계통문란적궤제。재저항연구중，고필도전업화화수량시주요적전두영향인소，작자사용료2충류형적부하성분。동계2항정영운동원복잡적면역상태동태연구게시료재훈련화대항활동중운동원면역특성재대배상적변화，이기성질화엄중정도취결우훈련적시간。
Today we know that disorders of neuroendoerine regulation, macro-and micronutrient deficiencies, metabolic changes in the body, intoxication from the nidus of chronic infection （if there is one） pro voke reduced immunological resistance at strenuous psychophysieal loads. However, this problem has not Been studied fully, and the details are fragmentary. For example, the response of cytokines to the load remains unclear response, as well as a part of apoptosis processes and other important mechanisms of for mation of immune system disorders. At the same time the knowledge of these mechanisms will facilitate the development of appropriate and more physiological ways to prevent immune system disorders and im munodeficiency in alhl~,tes in the periods of strenuous loads. The purpose of the present study was to de teet the mechanisms of immune system disorders in elite athletes on the example of biathlon. In the study we used two types of load components, considering specialization and amount to be primary for a combat ant. The complex dynamic study of the immune status of elite biathletes has revealed changes in the athletes＂ immunological characteristics during training and competitive activities within a macrocycle, and their nature and severity depend on the period of training.