心理科学进展
心理科學進展
심이과학진전
Advances In Psychological Science
2015年
6期
1000~1008
,共null页
抑郁症 额叶EEG偏侧化 额叶EEG不对称性 神经指标
抑鬱癥 額葉EEG偏側化 額葉EEG不對稱性 神經指標
억욱증 액협EEG편측화 액협EEG불대칭성 신경지표
depression;frontal EEG lateralization;frontal EEG asymmetry;neural index
额叶脑电活动的不对称性指即指额叶脑电图（electroencephalogram, EEG）偏侧化,其考察的是左侧额叶和右侧额叶alpha波（8～13 Hz）的活动。越来越多的研究证据表明,静息额叶EEG偏侧化程度与抑郁症密切相关。回顾国内外关于静息额叶EEG偏侧化与抑郁症之间关系的研究结果和现状,发现静息额叶EEG偏侧化程度与抑郁水平负相关,患有抑郁症个体的静息额叶 EEG 相对右侧化,伴随着右侧额叶更大的活动；从短期和长期而言,抑郁个体静息额叶EEG偏侧化具有稳定性；静息额叶EEG偏侧化对个体的抑郁水平具有预测作用。除此之外,静息额叶 EEG 偏侧化可能反应了背外侧前额叶皮层的活动,其中,左侧背外侧前额叶皮层可能在抑郁症的形成中起了一个主要的作用。未来的研究可致力于进一步探讨静息额叶EEG偏侧化预测抑郁症的神经机制、静息额叶 EEG 偏侧化对抑郁水平预测的可应用性,尝试通过训练（比如,正念冥想训练）来改变抑郁个体的静息额叶EEG偏侧化程度,进而缓解个体的抑郁水平。
額葉腦電活動的不對稱性指即指額葉腦電圖（electroencephalogram, EEG）偏側化,其攷察的是左側額葉和右側額葉alpha波（8～13 Hz）的活動。越來越多的研究證據錶明,靜息額葉EEG偏側化程度與抑鬱癥密切相關。迴顧國內外關于靜息額葉EEG偏側化與抑鬱癥之間關繫的研究結果和現狀,髮現靜息額葉EEG偏側化程度與抑鬱水平負相關,患有抑鬱癥箇體的靜息額葉 EEG 相對右側化,伴隨著右側額葉更大的活動；從短期和長期而言,抑鬱箇體靜息額葉EEG偏側化具有穩定性；靜息額葉EEG偏側化對箇體的抑鬱水平具有預測作用。除此之外,靜息額葉 EEG 偏側化可能反應瞭揹外側前額葉皮層的活動,其中,左側揹外側前額葉皮層可能在抑鬱癥的形成中起瞭一箇主要的作用。未來的研究可緻力于進一步探討靜息額葉EEG偏側化預測抑鬱癥的神經機製、靜息額葉 EEG 偏側化對抑鬱水平預測的可應用性,嘗試通過訓練（比如,正唸冥想訓練）來改變抑鬱箇體的靜息額葉EEG偏側化程度,進而緩解箇體的抑鬱水平。
액협뇌전활동적불대칭성지즉지액협뇌전도（electroencephalogram, EEG）편측화,기고찰적시좌측액협화우측액협alpha파（8～13 Hz）적활동。월래월다적연구증거표명,정식액협EEG편측화정도여억욱증밀절상관。회고국내외관우정식액협EEG편측화여억욱증지간관계적연구결과화현상,발현정식액협EEG편측화정도여억욱수평부상관,환유억욱증개체적정식액협 EEG 상대우측화,반수착우측액협경대적활동；종단기화장기이언,억욱개체정식액협EEG편측화구유은정성；정식액협EEG편측화대개체적억욱수평구유예측작용。제차지외,정식액협 EEG 편측화가능반응료배외측전액협피층적활동,기중,좌측배외측전액협피층가능재억욱증적형성중기료일개주요적작용。미래적연구가치력우진일보탐토정식액협EEG편측화예측억욱증적신경궤제、정식액협 EEG 편측화대억욱수평예측적가응용성,상시통과훈련（비여,정념명상훈련）래개변억욱개체적정식액협EEG편측화정도,진이완해개체적억욱수평。
The asymmetry of resting frontal activity was examined when differential activation of the alpha frequency band of left and right frontal cortex was found, i.e., frontal EEG lateralization. It had been showed largely that resting frontal EEG asymmetry was related to depression. Based on worldwide studies, we found that there was a negative correlation between resting frontal EEG asymmetry and depression level. Compared with individuals without depressive symptoms, those with depressive symptoms showed enhancement of right frontal activity. For depressive individuals, resting frontal EEG asymmetry was stable in the short and long run. That is to say, resting frontal EEG asymmetry predicted the risk of depression, which showed that frontal EEG asymmetry could be regarded as a neural index of depressive symptoms. In addition, resting frontal EEG asymmetry reflected the activation of dorsolateral prefrontal cortex, which might play a role in developing depressive symptoms. Future studies should focus on the neural mechanism of resting frontal EEG asymmetry predicting depression, the application of frontal EEG symmetry predicting depressive symptoms, and training methods （e.g., mindfulness training） to change the resting frontal EEG asymmetry of depressive individuals, relieving the depression level.
