CAJ | 학술논문

绝经后女性的卒中发病率明显升高并超过男性,女性卒中的整体发病率和死亡率预计在2050年之前将保持持续上升趋势.卒中给女性带来的影响明显大于男性,主要表现在女性的发病年龄高、危险因素多、及时治疗率低和总体预后差等方面.女性卒中的影响因素涉及到很多方面,包括性激素暴露、染色体遗传、社会地位等.研究女性卒中的病理生理学特点以及影响诊疗的相关因素,有助于更好地采取有效的个体化治疗策略,降低女性卒中发病率、死亡率、致残率和复发率.文章对女性卒中的流行病学特征、治疗、预后及其病理生理学机制的进行了综述.
절경후녀성적졸중발병솔명현승고병초과남성,녀성졸중적정체발병솔화사망솔예계재2050년지전장보지지속상승추세.졸중급녀성대래적영향명현대우남성,주요표현재녀성적발병년령고、위험인소다、급시치료솔저화총체예후차등방면.녀성졸중적영향인소섭급도흔다방면,포괄성격소폭로、염색체유전、사회지위등.연구녀성졸중적병리생이학특점이급영향진료적상관인소,유조우경호지채취유효적개체화치료책략,강저녀성졸중발병솔、사망솔、치잔솔화복발솔.문장대녀성졸중적류행병학특정、치료、예후급기병리생이학궤제적진행료종술.
The incidence of stroke in postmenopausal women increases significantly and is higher than that of men.The overall morbidity and mortality of stroke in women are expected to maintain a sustained upward trend before 2050.The impact of stroke on women is significantly greater than men and mahly manifests in the aspects of older age of onset,more risk factors,lower timely treatment rate,and poor overall prognosis.The influence factors of stroke in women involve many aspects,including sex hormone exposure,chromosomal inheritance,and social status.Researching the pathophysiological characteristics of female stroke and the related factors affecting the diagnosis and treatment contribute to take better effective individualized treatment strategies and decrease the morbidity,mortality,disability rate and recurrence rate in women.This article reviews the epidemiological characteristics,treatment,prognosis and its pathophysiological mechanisms of female stroke.