CAJ | 학술논문

目的分析胰十二指肠切除术后铜绿假单胞菌感染的危险因素,为临床预防及控制铜绿假单胞菌感染提供理论和实践依据.方法回顾性收集2011年6月至2014年6月上海交通大学医学院附属仁济医院胆胰外科胰十二指肠切除术后出现感染性并发症的患者共计119例.将分离出铜绿假单胞菌的患者作为观察组,未分离出铜绿假单胞菌的患者作为对照组.采用非条件Logistic回归,对铜绿假单胞菌感染的危险因素进行分析.结果 119例患者中分离出铜绿假单胞菌42例,占35.3％,其中以腹腔感染为主(38/42).多因素分析显示,糖尿病史、胰漏和术后使用碳青霉烯类抗生素是造成铜绿假单胞菌感染的独立危险因素.结论胰十二指肠切除术后具有较高的铜绿假单胞菌感染率.采取相应的干预措施,可能减少铜绿假单胞菌的发生率.
목적 분석이십이지장절제술후동록가단포균감염적위험인소,위림상예방급공제동록가단포균감염제공이론화실천의거.방법 회고성수집2011년6월지2014년6월상해교통대학의학원부속인제의원담이외과이십이지장절제술후출현감염성병발증적환자공계119례.장분리출동록가단포균적환자작위관찰조,미분리출동록가단포균적환자작위대조조.채용비조건Logistic회귀,대동록가단포균감염적위험인소진행분석.결과 119례환자중분리출동록가단포균42례,점35.3％,기중이복강감염위주(38/42).다인소분석현시,당뇨병사、이루화술후사용탄청매희류항생소시조성동록가단포균감염적독립위험인소.결론 이십이지장절제술후구유교고적동록가단포균감염솔.채취상응적간예조시,가능감소동록가단포균적발생솔.
Objective To evaluate the risk factors of Pseudomonas aeruginosa infection after pancreaticoduodenectomy (PD).Methods 119 patients who underwent PD with postoperative infectious complications were monitored for P.aeruginosa infection.The patients were grouped as P.aeruginosa infection and non-P.aeruginosa infection.Results 42 (35.3％) of the 119 patients were P.aeruginosa positive after PD.A history of diabetes mellitus,pancreatic fistula and use of carbapenems were independent factors predicting postoperative P.aeruginosa infection.Conclusions This study highlighted the high prevalence of P.aeruginosa infection after PD.Measures to combat P.aeruginosa infection (eg.good diabetic control,refined operative techniques and appropriate empirical antibiotic therapy) would likely to decrease the rate of P.aeruginosa infection.