CAJ | 학술논문

目的探讨肝门-空肠吻合术(Kasai手术)治疗Ⅲ型胆道闭锁的临床疗效.方法对开封市儿童医院2009年1月至2013年12月收治并采用同一治疗方案进行Kasai手术的Ⅲ型胆道闭锁患者进行回顾性分析.结果进行Kasai手术的48例有42例(87.5％)获得完整随访.术后有31例黄疸消退,总黄疸清除率为73.8％.总胆管炎发生率为47.6％(20/42).术后2年生存率无胆管炎组为86.4％ (19/22),轻度胆管炎组为75.0％ (9/12),重度胆管炎组为25.0％ (2/8).三组差异有统计学意义(P＜0.05).结论肝门-空肠吻合术(Kasai手术)是治疗Ⅲ型胆道闭锁的有效术式.患者存活率与术后胆汁引流量及有无胆管炎相关.
목적 탐토간문-공장문합술(Kasai수술)치료Ⅲ형담도폐쇄적림상료효.방법 대개봉시인동의원2009년1월지2013년12월수치병채용동일치료방안진행Kasai수술적Ⅲ형담도폐쇄환자진행회고성분석.결과 진행Kasai수술적48례유42례(87.5％)획득완정수방.술후유31례황달소퇴,총황달청제솔위73.8％.총담관염발생솔위47.6％(20/42).술후2년생존솔무담관염조위86.4％ (19/22),경도담관염조위75.0％ (9/12),중도담관염조위25.0％ (2/8).삼조차이유통계학의의(P＜0.05).결론 간문-공장문합술(Kasai수술)시치료Ⅲ형담도폐쇄적유효술식.환자존활솔여술후담즙인류량급유무담관염상관.
Objective To determine the clinical effects of type Ⅲ biliary atresia treated by hepatojejunostomy (Kasai procedure).Methods A retrospective study was performed on patients with type Ⅲ biliary atresia treated in our hospital between January 2009 to December 2013.Results The follow-up data were completed in 42 patients out of 48 patients (87.5％) who underwent Kasai procedure for type Ⅲ biliary atresia.The jaundice disappeared in 31 of 42 patients (73.8％).The rate of patients having cholangitis was 47.6％.There were significant differences in the 2-year survival among the groups of patients with mild cholangitis (75.0％,9/12),serious cholangitis (25.0％,2/8) and without cholangitis (86.4％,19/22) (P ＜ 0.05).Conclusions Hepatojejunostomy (Kasai procedure) is an effective operation to treat type Ⅲ biliary atresia.Our data suggested that the survival rates were related to the degree of bile drainage and cholangitis post surgery.