中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
8期
1088-1091
,共4页
药品不良反应%注射剂型%静脉滴注%抗感染药%合理用药
藥品不良反應%註射劑型%靜脈滴註%抗感染藥%閤理用藥
약품불량반응%주사제형%정맥적주%항감염약%합리용약
ADR%Injection preparation%Intravenous route%Antibacterial drugs%Rational drug use
目的:了解药品不良反应( adverse drug reaction,ADR)发生的特点及规律,为临床合理用药提供参考. 方法:对首钢水钢总医院(以下简称"我院")2007-2013年收集上报至全国ADR监测网络的420例ADR报告进行回顾性分析. 结果:420例ADR中,女性患者发生率(223例,占53. 10%)略高于男性患者(197例,占46. 90%);注射剂型(443例次,占合计479例次的92. 48%)及静脉滴注给药(410例次,占合计479例次的85. 59%)最容易引发ADR;抗感染药引发的ADR病例数最多(247例次,占合计475例次的52. 00%);ADR累及器官和(或)系统以皮肤及其附件损害最为常见( 258例次,占合计592例次的43. 58%). 结论:ADR的发生与多种因素有关,临床应加强ADR报告与监测工作,提高合理用药水平,以减少ADR的发生,保障患者用药安全.
目的:瞭解藥品不良反應( adverse drug reaction,ADR)髮生的特點及規律,為臨床閤理用藥提供參攷. 方法:對首鋼水鋼總醫院(以下簡稱"我院")2007-2013年收集上報至全國ADR鑑測網絡的420例ADR報告進行迴顧性分析. 結果:420例ADR中,女性患者髮生率(223例,佔53. 10%)略高于男性患者(197例,佔46. 90%);註射劑型(443例次,佔閤計479例次的92. 48%)及靜脈滴註給藥(410例次,佔閤計479例次的85. 59%)最容易引髮ADR;抗感染藥引髮的ADR病例數最多(247例次,佔閤計475例次的52. 00%);ADR纍及器官和(或)繫統以皮膚及其附件損害最為常見( 258例次,佔閤計592例次的43. 58%). 結論:ADR的髮生與多種因素有關,臨床應加彊ADR報告與鑑測工作,提高閤理用藥水平,以減少ADR的髮生,保障患者用藥安全.
목적:료해약품불량반응( adverse drug reaction,ADR)발생적특점급규률,위림상합리용약제공삼고. 방법:대수강수강총의원(이하간칭"아원")2007-2013년수집상보지전국ADR감측망락적420례ADR보고진행회고성분석. 결과:420례ADR중,녀성환자발생솔(223례,점53. 10%)략고우남성환자(197례,점46. 90%);주사제형(443례차,점합계479례차적92. 48%)급정맥적주급약(410례차,점합계479례차적85. 59%)최용역인발ADR;항감염약인발적ADR병례수최다(247례차,점합계475례차적52. 00%);ADR루급기관화(혹)계통이피부급기부건손해최위상견( 258례차,점합계592례차적43. 58%). 결론:ADR적발생여다충인소유관,림상응가강ADR보고여감측공작,제고합리용약수평,이감소ADR적발생,보장환자용약안전.
OBJECTIVE:To investigate the regularity and characteristics of adverse drug reactions ( ADR) ,and to provide reference for rational drug use in clinic. METHODS: Retrospective analysis was conducted on 420 ADR reports collected in Shougang Shuigang General Hospital ( hereinafter referred to as "our hospital") from Nationwide Adverse Drug Reaction Monitoring Network during 2007-2013. RESULTS: Of the 420 ADR cases, female patients (223 cases, 53. 10%) showed a higher incidence than male patients(197 cases, 46. 90%);the ADR cases induced by injection preparation(443 cases,accounting for 92. 48% of the total 479 cases) and intravenous route(410 cases, accounting for 85. 59% of the total 479 cases) were the most common; the main category of drugs that induced ADR was antibacterial drugs(247 cases, accounting for 52. 00% of the total 475 cases) . Lesions of skin and its appendages were the most common clinical manifestations of ADR(258 cases, accounting for 43. 58% of the total 592 cases). CONCLUSIONS:The occurrence of ADR cases is related with a variety of factors. Report and monitoring of ADR should be strengthened and the level of rational drug use should be improved so as to reduce the occurrence of ADR and ensure the safety of drug use for patient.
