中国医药科学
中國醫藥科學
중국의약과학
China Medicine and Pharmacy
2015年
14期
153-155
,共3页
[关健词]脑梗死%半胱氨酸%缺血性血管
[關健詞]腦梗死%半胱氨痠%缺血性血管
[관건사]뇌경사%반광안산%결혈성혈관
Cerebral infarction%Cysteine%Ischemic vascular
目的 探索分析在接受蛋氨酸负荷试验(MLT)后血浆同型半胱氨酸(Hcy)对脑梗死患者再发缺血性血管事件的具体作用和影响.方法 选择我院收治的血浆空腹Hcy(FHcy)水平正常的脑梗死患者作为研究对象并进行分组研究,均接受蛋氨酸负荷试验(MLT),将试验后的高Hcy血症(PHHcy)组和非高Hcy血症(NPHHcy) 组患者的缺血性血管事件发生情况进行对比分析.结果 负荷后高同型半胱氨酸血症(PHHcy)组患者发生脑梗死脑缺血、冠状动脉综合征、血管栓塞等缺血性血管事件发生率为70.69%,显著高于负荷后非高同型半胱氨酸血症组(NPHHcy)的36.67%(P<0.05).结论 高Hcy血症(PHHcy)可以作为导致脑梗死患者再发缺血性血管事件的独立危险因素,在实际操作中要引起高度重视.
目的 探索分析在接受蛋氨痠負荷試驗(MLT)後血漿同型半胱氨痠(Hcy)對腦梗死患者再髮缺血性血管事件的具體作用和影響.方法 選擇我院收治的血漿空腹Hcy(FHcy)水平正常的腦梗死患者作為研究對象併進行分組研究,均接受蛋氨痠負荷試驗(MLT),將試驗後的高Hcy血癥(PHHcy)組和非高Hcy血癥(NPHHcy) 組患者的缺血性血管事件髮生情況進行對比分析.結果 負荷後高同型半胱氨痠血癥(PHHcy)組患者髮生腦梗死腦缺血、冠狀動脈綜閤徵、血管栓塞等缺血性血管事件髮生率為70.69%,顯著高于負荷後非高同型半胱氨痠血癥組(NPHHcy)的36.67%(P<0.05).結論 高Hcy血癥(PHHcy)可以作為導緻腦梗死患者再髮缺血性血管事件的獨立危險因素,在實際操作中要引起高度重視.
목적 탐색분석재접수단안산부하시험(MLT)후혈장동형반광안산(Hcy)대뇌경사환자재발결혈성혈관사건적구체작용화영향.방법 선택아원수치적혈장공복Hcy(FHcy)수평정상적뇌경사환자작위연구대상병진행분조연구,균접수단안산부하시험(MLT),장시험후적고Hcy혈증(PHHcy)조화비고Hcy혈증(NPHHcy) 조환자적결혈성혈관사건발생정황진행대비분석.결과 부하후고동형반광안산혈증(PHHcy)조환자발생뇌경사뇌결혈、관상동맥종합정、혈관전새등결혈성혈관사건발생솔위70.69%,현저고우부하후비고동형반광안산혈증조(NPHHcy)적36.67%(P<0.05).결론 고Hcy혈증(PHHcy)가이작위도치뇌경사환자재발결혈성혈관사건적독립위험인소,재실제조작중요인기고도중시.
Objective To explore and analyze specific effect and influence of plasma homocysteine (Hcy) after methionine Loading Test (MLT) in recurrent ischemic vascular events of patients with cerebral infarction. Methods Patients with cerebral infarction who were admitted to our hospital with normal level of fasting Hcy (FHcy) were selected as research subjects, and all of them were received MLT. Ischemic vascular events of High Hcy hyperlipidemia (PHHcy) group and Non-High Hcy hyperlipidemia (NPHHcy) were compared and analyzed. ResultsThe occurrence rate of ischemic vascular events including cerebral infarction ischemia, coronary syndrome and vascular embolization of PHHcy group after loading test was 70.69%, which was significantly higher than 36.67% of NPHHcy after loading test (P<0.05). Conclusion PHHcy can be an independent risk factor that leads to recurrent ischemic vascular events of patients with cerebral infarction, which should draw great attentions in clinical operation.
