CAJ | 학술논문

目的:了解河南省肿瘤医院(以下简称"我院")抗菌药物专项整治活动中住院患者抗菌药物应用情况及趋势. 方法:回顾性分析我院2011-2013年抗菌药物应用品种、销售金额、用药频度( DDDs)、限定日费用及抗菌药物使用强度( antibiotics use density,AUD)、使用率等. 结果:抗菌药物销售金额在2012年有所增长,增幅为13. 75%,但在2013年开始下降,降幅为6. 2%;2011-2013年抗菌药物DDDs基本稳定,平均增幅为0. 81%;住院患者人均抗菌药物费用略有增加,增幅为4. 91%;住院患者抗菌药物限定日费用在2012年有所增长,增幅为13. 12%,但2013年开始下降,降幅为7. 18%;住院患者人均抗菌药物品种数基本稳定,增幅为0. 54%;抗菌药物使用率逐年下降,平均降幅为13. 89%;AUD逐年下降,平均降幅为11. 17%. 3年来,第3代头孢菌素的DDDs排序均居第1位,构成比分别为28. 57%、25. 09%、29. 29%;非限制使用级抗菌药物的DDDs明显增加,平均增幅为48. 62%;剂型以注射剂为主,其DDDs构成比分别为91. 48%、90. 54%和88. 5%,平均降幅0. 85%. 结论:抗菌药物专项整治活动中我院抗菌药物临床应用总体指标合理,抗菌药物应用更趋合理.
목적:료해하남성종류의원(이하간칭"아원")항균약물전항정치활동중주원환자항균약물응용정황급추세. 방법:회고성분석아원2011-2013년항균약물응용품충、소수금액、용약빈도( DDDs)、한정일비용급항균약물사용강도( antibiotics use density,AUD)、사용솔등. 결과:항균약물소수금액재2012년유소증장,증폭위13. 75%,단재2013년개시하강,강폭위6. 2%;2011-2013년항균약물DDDs기본은정,평균증폭위0. 81%;주원환자인균항균약물비용략유증가,증폭위4. 91%;주원환자항균약물한정일비용재2012년유소증장,증폭위13. 12%,단2013년개시하강,강폭위7. 18%;주원환자인균항균약물품충수기본은정,증폭위0. 54%;항균약물사용솔축년하강,평균강폭위13. 89%;AUD축년하강,평균강폭위11. 17%. 3년래,제3대두포균소적DDDs배서균거제1위,구성비분별위28. 57%、25. 09%、29. 29%;비한제사용급항균약물적DDDs명현증가,평균증폭위48. 62%;제형이주사제위주,기DDDs구성비분별위91. 48%、90. 54%화88. 5%,평균강폭0. 85%. 결론:항균약물전항정치활동중아원항균약물림상응용총체지표합리,항균약물응용경추합리.
OBJECTIVE:To investigate the application tendency for inpatients of antibacterial drugs in the special rectification activity in Henan Cancer Hospital ( hereinafter referred to as "our hospital") . METHODS: By retrospective method, the utilization of antibacterial drugs in our hospital during 2011-2013 was analyzed in respect of application of drug types, consumption sum, DDDs, DDC and AUD etc. RESULTS: The consumption sum of antibacterial drugs increased by 13. 75% in 2012 while decreased by 6. 2% in 2013 . The DDDs of antibacterial drugs was relatively stable during 2011-2013, the average increase rate was 0. 81%. For the inpatient, per capita expenses of antibacterial drugs increased by 4. 91%; per capita expenses daily of antibacterial drugs increased by 13. 12% in 2012 while decreased by 7. 18% in 2013 . The average number of antibacterial drugs consumption was relatively stable, increased by 0. 54%. The utilization ratio of antibacterial drugs for inpatients had decreased annually by 13. 89%. AUD averagely decreased by 11. 17% year by year. In terms of DDDs, third generation cephalosporins ranked at the first place during the three years, and the constituent ratio was respectively 28. 57%、25. 09%、29. 29%;DDDs of antibacterial drugs of non restricted grade increased by 48. 62%. The main dosage form was injection, the constituent ratio of DDDs was respectively 91. 48%、90. 54% and 88. 5%, averagely decreased by 0. 85%.CONCLUSIONS:After the special rectification activity, the overall index of clinical application of antibacterial drugs is reasonable and the application of antibacterial drugs has become more rational.