中国医药科学
中國醫藥科學
중국의약과학
China Medicine and Pharmacy
2015年
14期
180-182
,共3页
汤晓催%李文绍%谢日深%赵志敏%梁孟
湯曉催%李文紹%謝日深%趙誌敏%樑孟
탕효최%리문소%사일심%조지민%량맹
降钙素原%急性发热%抗生素应用%指导价值
降鈣素原%急性髮熱%抗生素應用%指導價值
강개소원%급성발열%항생소응용%지도개치
Procalcitonin%Acute fever%Antibiotics%Guiding value
目的 探讨降钙素原在基层医院急性发热患者中应用抗生素的指导价值.方法 随机将200例急性呼吸道感染性发热患者分为常规组与PCT组各100例.常规组在进行常规监测后根据抗生素应用标准使用抗生素治疗,PCT组在常规组的监测基础上进行PCT值检测,并在PCT值指导下决定用药方案及使用抗生素.观察两组的抗生素使用率及合理率、失误率、滥用率,以及抗生素使用时间及治疗费用等情况. 结果 两组患者临床治疗效果方面比较(P>0.05);观察组的治疗总时间为(6.13±1.17)d,对照组为(8.03±2.43)d,两组比较(P<0.05).PCT组在抗生素使用率、持续使用时间以及抗生素费用方面均明显少于常规组(P<0.05).细菌感染患者的PCT、CRP及WBC均较病毒感染、非感染患者高(P<0.05).结论 通过检测患者体内的PCT值,可以精准判断患者属于细菌发热或非细菌发热,指导使用抗生素,可使抗生素得到合理的使用,显著改善抗生素滥用的现状,节约医疗资源,降低医疗费用.
目的 探討降鈣素原在基層醫院急性髮熱患者中應用抗生素的指導價值.方法 隨機將200例急性呼吸道感染性髮熱患者分為常規組與PCT組各100例.常規組在進行常規鑑測後根據抗生素應用標準使用抗生素治療,PCT組在常規組的鑑測基礎上進行PCT值檢測,併在PCT值指導下決定用藥方案及使用抗生素.觀察兩組的抗生素使用率及閤理率、失誤率、濫用率,以及抗生素使用時間及治療費用等情況. 結果 兩組患者臨床治療效果方麵比較(P>0.05);觀察組的治療總時間為(6.13±1.17)d,對照組為(8.03±2.43)d,兩組比較(P<0.05).PCT組在抗生素使用率、持續使用時間以及抗生素費用方麵均明顯少于常規組(P<0.05).細菌感染患者的PCT、CRP及WBC均較病毒感染、非感染患者高(P<0.05).結論 通過檢測患者體內的PCT值,可以精準判斷患者屬于細菌髮熱或非細菌髮熱,指導使用抗生素,可使抗生素得到閤理的使用,顯著改善抗生素濫用的現狀,節約醫療資源,降低醫療費用.
목적 탐토강개소원재기층의원급성발열환자중응용항생소적지도개치.방법 수궤장200례급성호흡도감염성발열환자분위상규조여PCT조각100례.상규조재진행상규감측후근거항생소응용표준사용항생소치료,PCT조재상규조적감측기출상진행PCT치검측,병재PCT치지도하결정용약방안급사용항생소.관찰량조적항생소사용솔급합리솔、실오솔、람용솔,이급항생소사용시간급치료비용등정황. 결과 량조환자림상치료효과방면비교(P>0.05);관찰조적치료총시간위(6.13±1.17)d,대조조위(8.03±2.43)d,량조비교(P<0.05).PCT조재항생소사용솔、지속사용시간이급항생소비용방면균명현소우상규조(P<0.05).세균감염환자적PCT、CRP급WBC균교병독감염、비감염환자고(P<0.05).결론 통과검측환자체내적PCT치,가이정준판단환자속우세균발열혹비세균발열,지도사용항생소,가사항생소득도합리적사용,현저개선항생소람용적현상,절약의료자원,강저의료비용.
Objective To investigate the application of procalcitonin guidance value of antibiotics in acute febrile patients of primary hospital. Methods 200 cases with acute respiratory infection and fever were allocated into a conventional group and a PCT group,100 cases in each group.After carrying out routine monitoring of the conventional group of antibiotics used in accordance with standard antibiotics,the PCT group values detected in the monitoring group further received PCT value guidance.Antibiotic usage and reasonable rates,the error rate,the abuse rate,and the time and cost of treatment of antibiotic use and so on were observed.Results The clinical results between the two groups of patients (P>0.05);The total time of the treatment group was (6.13±1.17)d,the control group was (8.03±2.43) d,difference between the two groups (P<0.05).Antibiotic usage,time,and costs continued use of antibiotics in the PCT group were significantly less than those in the conventional group (P<0.05).PCT in patients with bacterial infections,CRP and WBC compared with a viral infection,high non-infected patients(P<0.05).Conclusion By detecting the patient PCT values,you can accurately determine a patient belongs to bacteria or bacterial fever,to guide the use of antibiotics,the rational use of antibiotics can significantly improve the status of the abuse of antibiotics,saving medical resources,reduce health care costs.
