中国医药科学
中國醫藥科學
중국의약과학
China Medicine and Pharmacy
2015年
14期
119-122
,共4页
腹腔镜%结肠癌切除术%高危结肠癌
腹腔鏡%結腸癌切除術%高危結腸癌
복강경%결장암절제술%고위결장암
Laparoscopy%Resection of colonic cancer%Colonic cancer in high-risk
目的 探讨腹腔镜结肠切除术应用于高危结肠癌患者治疗的临床价值.方法 60例高危结肠癌患者按手术方法分为两组,LCR组30例行腹腔镜下结肠癌切除术,对照组30例行开放结肠切除术.观察两组手术情况、围手术期并发症、淋巴结清扫数量、复发率. 结果 LCR组平均手术时间与OCR组比较差异均无统计学意义(P>0.05),LCR组术中出血量、住院时间、肛门排气时间、术后前3d引流量、引流管拔除时间明显少于OCR组(P<0.05).LCR组围术期并发症发生率显著低于OCR组(13.3% vs 43.3%,P<0.01).LCR组TNMⅡ期及Ⅲ期淋巴结清扫数目均明显多于OCR组(P<0.05),术后复发率3.3%显著低于OCR组20.0%,差异有统计学意义(P<0.05),3年内生存率100.0%与OCR组93.3%比较差异无统计学意义(P>0.05).结论 腹腔镜下结肠癌切除术治疗高危结肠癌安全有效,符合肿瘤根治原则.
目的 探討腹腔鏡結腸切除術應用于高危結腸癌患者治療的臨床價值.方法 60例高危結腸癌患者按手術方法分為兩組,LCR組30例行腹腔鏡下結腸癌切除術,對照組30例行開放結腸切除術.觀察兩組手術情況、圍手術期併髮癥、淋巴結清掃數量、複髮率. 結果 LCR組平均手術時間與OCR組比較差異均無統計學意義(P>0.05),LCR組術中齣血量、住院時間、肛門排氣時間、術後前3d引流量、引流管拔除時間明顯少于OCR組(P<0.05).LCR組圍術期併髮癥髮生率顯著低于OCR組(13.3% vs 43.3%,P<0.01).LCR組TNMⅡ期及Ⅲ期淋巴結清掃數目均明顯多于OCR組(P<0.05),術後複髮率3.3%顯著低于OCR組20.0%,差異有統計學意義(P<0.05),3年內生存率100.0%與OCR組93.3%比較差異無統計學意義(P>0.05).結論 腹腔鏡下結腸癌切除術治療高危結腸癌安全有效,符閤腫瘤根治原則.
목적 탐토복강경결장절제술응용우고위결장암환자치료적림상개치.방법 60례고위결장암환자안수술방법분위량조,LCR조30례행복강경하결장암절제술,대조조30례행개방결장절제술.관찰량조수술정황、위수술기병발증、림파결청소수량、복발솔. 결과 LCR조평균수술시간여OCR조비교차이균무통계학의의(P>0.05),LCR조술중출혈량、주원시간、항문배기시간、술후전3d인류량、인류관발제시간명현소우OCR조(P<0.05).LCR조위술기병발증발생솔현저저우OCR조(13.3% vs 43.3%,P<0.01).LCR조TNMⅡ기급Ⅲ기림파결청소수목균명현다우OCR조(P<0.05),술후복발솔3.3%현저저우OCR조20.0%,차이유통계학의의(P<0.05),3년내생존솔100.0%여OCR조93.3%비교차이무통계학의의(P>0.05).결론 복강경하결장암절제술치료고위결장암안전유효,부합종류근치원칙.
Objective To explore the clinical effect of laparoscopic colectomy in the treatment of colonic cancer in high-risk patients.Methods 60 cases of patients with colonic cancer were divided into two groups.The LCR group(n=30) was managed laparoscopic colectomy and the OCR group(n=30) were traditional open operation.The operation condition,preoperative complications,amount of lymph node scavenged,and the relapse rate of the 2 groups were contrasted.ResultsThe operation period of LCR group with no difference compared to OCR group(P>0.05),And the hospital stays,period of passage of gas by anus,the drainage volume post 3 days of operation,the period of drainage tube extraction and the intraoperative bleeding volume of LCR group was significant less than that of OCR group (P<0.05).There was significant difference in complication and the amount of lymph nodes scavenged of patients between 2 groups(13.3% vs 43.3%,P<0.01).The amount of lymph nodes scavenged of patients in TNM Ⅱ and Ⅲ of LCR group was more than that of OCR control group.The relapse rate in LCR group (3.3%) was lower than that in OCR group(20.0%),and the survival rate in 3 years(100.0%) of LCR group with no difference compared to OCR group(93.3%)(P>0.05).Conclusion Laparoscopic colectomy can be successfully performed for high-risk colonic cancer,with all the advantages of minimally surgery.