四川医学
四川醫學
사천의학
Sichuan Medical Journal
2015年
8期
1084-1087
,共4页
杨涛毅%郭丽春%陈桂华%张彤
楊濤毅%郭麗春%陳桂華%張彤
양도의%곽려춘%진계화%장동
儿童%难治性%社区获得性肺炎%病毒
兒童%難治性%社區穫得性肺炎%病毒
인동%난치성%사구획득성폐염%병독
children%refractory%community-acquired pneumonia%viral
目的 通过住院患儿社区获得性肺炎( CAP)和难治性社区获得性肺炎( RCAP)病毒感染临床特点的比较,了解成都地区病毒性RCAP的住院儿童的感染状况和特点,为RCAP的预防和治疗提供理论依据. 方法 对391 例RCAP和CAP住院患儿痰液进行流感病毒、副流感病毒、呼吸道合胞病毒、冠状病毒、人偏肺病毒、人博卡病毒、人腺病毒、人鼻病毒和肠道病毒核酸检测及EB病毒和巨细胞病毒IgM抗体检测,痰液和血清细菌学和非典型病原体的检测. 结果在391例住院肺炎患儿检测出病毒检测阳性24. 81%,110株病毒. 在冬季病毒检出率最高为43. 58%,不同性别患者之间病毒检出率差异. 193例RCAP病毒检测阳性患儿20. 73%(47株),腺病毒、人偏肺病毒和EB病毒感染占前3位,混合感染占78. 72%. 结论 病毒感染是RCAP主要致病菌之一,病毒在RCAP中有较低的检出率,混合感染和病毒感染种类不同是导致RCAP的原因之一.
目的 通過住院患兒社區穫得性肺炎( CAP)和難治性社區穫得性肺炎( RCAP)病毒感染臨床特點的比較,瞭解成都地區病毒性RCAP的住院兒童的感染狀況和特點,為RCAP的預防和治療提供理論依據. 方法 對391 例RCAP和CAP住院患兒痰液進行流感病毒、副流感病毒、呼吸道閤胞病毒、冠狀病毒、人偏肺病毒、人博卡病毒、人腺病毒、人鼻病毒和腸道病毒覈痠檢測及EB病毒和巨細胞病毒IgM抗體檢測,痰液和血清細菌學和非典型病原體的檢測. 結果在391例住院肺炎患兒檢測齣病毒檢測暘性24. 81%,110株病毒. 在鼕季病毒檢齣率最高為43. 58%,不同性彆患者之間病毒檢齣率差異. 193例RCAP病毒檢測暘性患兒20. 73%(47株),腺病毒、人偏肺病毒和EB病毒感染佔前3位,混閤感染佔78. 72%. 結論 病毒感染是RCAP主要緻病菌之一,病毒在RCAP中有較低的檢齣率,混閤感染和病毒感染種類不同是導緻RCAP的原因之一.
목적 통과주원환인사구획득성폐염( CAP)화난치성사구획득성폐염( RCAP)병독감염림상특점적비교,료해성도지구병독성RCAP적주원인동적감염상황화특점,위RCAP적예방화치료제공이론의거. 방법 대391 례RCAP화CAP주원환인담액진행류감병독、부류감병독、호흡도합포병독、관상병독、인편폐병독、인박잡병독、인선병독、인비병독화장도병독핵산검측급EB병독화거세포병독IgM항체검측,담액화혈청세균학화비전형병원체적검측. 결과재391례주원폐염환인검측출병독검측양성24. 81%,110주병독. 재동계병독검출솔최고위43. 58%,불동성별환자지간병독검출솔차이. 193례RCAP병독검측양성환인20. 73%(47주),선병독、인편폐병독화EB병독감염점전3위,혼합감염점78. 72%. 결론 병독감염시RCAP주요치병균지일,병독재RCAP중유교저적검출솔,혼합감염화병독감염충류불동시도치RCAP적원인지일.
Objective To understand the common viral infections of Community acquired pneumonia children hospitalized in Chengdu and provide theoretical basis for the prevention. Methods Collecting 391 specimens of RCAP and CAP children from the hospitals in Chengdu during November,2012 to October,2014. Common respiratory viruses including influenza virus,parainflu-enza virus,respiratory syncytial virus,coronavirus,human metapneumovirus,human boca virus,human adenovirus,human rhinovi-rus and enterovirus were detected in 391 sputum specimens simultaneous-Resultsly by multiplex RT- PCR. EBVCA-IgG , EB-VEA-Ig M and CMV-IgM were detected by ELISA. Results Totally 97 positive samples were identified from 391 specimens,the positive rate was 24. 81% (92/391) ,The positive rate was 20. 73% (40/193) in RCAP children, in which,the mostly detected human metapneumovirus,human adenovirus and EB-Viral. The highest detection rate of virus in winter was 43. 58% and the de-tection rate was not statistically significant between children of different gender. 193 cases of children with RCAP get viral positive identification with other pathogens at the same time were for 34cases (78. 72%). Conclusion Virall infection is one of the CAP and RCAP children hospitalization main pathogens. Viral infection of RCAP had a lower detection rate. Human metapneumovirus, adenovirus, and EB-Viral rhinovirus were the main pathogens leading to the RCAP in Chengdu,mixed infections were common.
