中国医药科学
中國醫藥科學
중국의약과학
China Medicine and Pharmacy
2015年
14期
17-19
,共3页
脓毒症%血小板减少症%预后%危险因素
膿毒癥%血小闆減少癥%預後%危險因素
농독증%혈소판감소증%예후%위험인소
Sepsis%Thrombocytopenia%Prognosis%Risk factors
目的 探讨脓毒症相关性血小板减少症的相关危险因素及其对患者预后的影响. 方法 选取2012年7月~2014年7月于我院接受治疗的80例脓毒症患者作为研究对象,并按照是否伴血小板减少症将其分为A、B两组,A组为血小板减少组,n=30,B组为血小板非减少组,n=50,分析两组患者的一般资料及相关实验室指标、感染控制率及1个月病死率,采取多元回归分析法,总结脓毒症相关性血小板减少症独立危险因素,分析其与患者预后的关系.结果 A组患者血小板减少最低值为(39.1±22.0)×109/L,明显低于B组,其C反应蛋白水平、降钙素原水平分别为(112.4±68.1)mg/L、(7.2±6.1)ng/mL,均高于B组(P<0.05);多元回归分析结果提示:血小板减少<3×109/L、血小板持续减少>1周、脓毒症休克与多器官衰竭为脓毒症相关性血小板减少症的独立危险因素.结论 脓毒症患者出现持续性血小板减少、脓毒症休克及多器官衰竭表现是预示患者病情危重的主要指标,提示患者预后水平差,死亡率高.
目的 探討膿毒癥相關性血小闆減少癥的相關危險因素及其對患者預後的影響. 方法 選取2012年7月~2014年7月于我院接受治療的80例膿毒癥患者作為研究對象,併按照是否伴血小闆減少癥將其分為A、B兩組,A組為血小闆減少組,n=30,B組為血小闆非減少組,n=50,分析兩組患者的一般資料及相關實驗室指標、感染控製率及1箇月病死率,採取多元迴歸分析法,總結膿毒癥相關性血小闆減少癥獨立危險因素,分析其與患者預後的關繫.結果 A組患者血小闆減少最低值為(39.1±22.0)×109/L,明顯低于B組,其C反應蛋白水平、降鈣素原水平分彆為(112.4±68.1)mg/L、(7.2±6.1)ng/mL,均高于B組(P<0.05);多元迴歸分析結果提示:血小闆減少<3×109/L、血小闆持續減少>1週、膿毒癥休剋與多器官衰竭為膿毒癥相關性血小闆減少癥的獨立危險因素.結論 膿毒癥患者齣現持續性血小闆減少、膿毒癥休剋及多器官衰竭錶現是預示患者病情危重的主要指標,提示患者預後水平差,死亡率高.
목적 탐토농독증상관성혈소판감소증적상관위험인소급기대환자예후적영향. 방법 선취2012년7월~2014년7월우아원접수치료적80례농독증환자작위연구대상,병안조시부반혈소판감소증장기분위A、B량조,A조위혈소판감소조,n=30,B조위혈소판비감소조,n=50,분석량조환자적일반자료급상관실험실지표、감염공제솔급1개월병사솔,채취다원회귀분석법,총결농독증상관성혈소판감소증독립위험인소,분석기여환자예후적관계.결과 A조환자혈소판감소최저치위(39.1±22.0)×109/L,명현저우B조,기C반응단백수평、강개소원수평분별위(112.4±68.1)mg/L、(7.2±6.1)ng/mL,균고우B조(P<0.05);다원회귀분석결과제시:혈소판감소<3×109/L、혈소판지속감소>1주、농독증휴극여다기관쇠갈위농독증상관성혈소판감소증적독립위험인소.결론 농독증환자출현지속성혈소판감소、농독증휴극급다기관쇠갈표현시예시환자병정위중적주요지표,제시환자예후수평차,사망솔고.
Objective To explore the related factors of disease of sepsis associated thrombocytopenia and the influence on prognosis of patients of sepsis.Methods 80 cases of sepsis patients from July 2012 to July 2014 were treated in our hospital as the research object, according to whether associated with thrombocytopenia were divided into group A, B, group A was reduction group, plateletn=30, group B was reduced platelet group,n=50, analysis of general data and related laboratory index, control rate of infection and mortality rate in1 month of two groups, adopted the multiple regression analysis, summarized sepsis associated thrombocytopenia independent risk factors, analysis of the relationship with prognosis of patients. ResultsIn group A, patients with thrombocytopenia minimum value was (39.1±22)×109/L, was significantly lower than that in group B, the level of C reactive protein, procalcitonin levels in group A were (112.4±68.1) mg/L, (7.2±6.1) ng/mL, were higher than those in group B (P<0.05); multiple regression analysis indicated: Thrombocytopenia<3×109/L, platelet sustained reduction of >1 week, septic shock and multiple organ failure were the independent risk of sepsis associated thrombocytopenia factors.Conclusion Patients with sepsis with persistent thrombocytopenia, septic shock and multiple organ failure performance is the main indicator of critically ill of prognosis of patients, suggests prognosis of patients with poor level, the mortality rate is high.
