中国医药科学
中國醫藥科學
중국의약과학
China Medicine and Pharmacy
2015年
14期
13-16
,共4页
廖全忠%曾洁嫦%崔健%杨权
廖全忠%曾潔嫦%崔健%楊權
료전충%증길항%최건%양권
中央型肺癌%支气管镜%局部化疗%静脉化疗%临床价值
中央型肺癌%支氣管鏡%跼部化療%靜脈化療%臨床價值
중앙형폐암%지기관경%국부화료%정맥화료%림상개치
Central lung cancer%Bronchoscopy%Local chemotherapy%Systemic chemotherapy%Clinical value
目的 本研究就经支气管镜下局部化疗应用于中央型肺癌治疗中的临床价值进行了浅显的研究和探讨,从而为临床上提供可靠的数据.方法 选择我院自2012年1月~2014年1月收治的中央型肺癌患者70例,作为研究对象将其平均分为观察组和对照组,两组患者均35例,观察组行经支气管镜下局部化疗,对照组行全身静脉化疗,在经过一个疗程的治疗后,对两组患者的气道狭窄治疗效果,不良反应发生率及生活质量评分进行观察和统计.结果 观察组的35例患者接受经支气管镜下局部化疗后的临床总有效率为97.14%;对照组的35例患者接受全身静脉化疗后的临床总有效率为82.86%,差异有统计学意义(P<0.05);接受经支气管镜下局部化疗治疗期间共发生不良反应1例,占5.71%;对照组的35例患者接受全身静脉化疗治疗期间共发生不良反应8例,占22.86%,差异有统计学意义(P<0.05);生活质量评分明显高于对照组35例接受全身静脉化疗后的生活质量评分(P<0.05). 结论 经支气管镜下局部化疗应用于中央型肺癌治疗中的效果显著,有效改善了患者的生活质量,值得推广.
目的 本研究就經支氣管鏡下跼部化療應用于中央型肺癌治療中的臨床價值進行瞭淺顯的研究和探討,從而為臨床上提供可靠的數據.方法 選擇我院自2012年1月~2014年1月收治的中央型肺癌患者70例,作為研究對象將其平均分為觀察組和對照組,兩組患者均35例,觀察組行經支氣管鏡下跼部化療,對照組行全身靜脈化療,在經過一箇療程的治療後,對兩組患者的氣道狹窄治療效果,不良反應髮生率及生活質量評分進行觀察和統計.結果 觀察組的35例患者接受經支氣管鏡下跼部化療後的臨床總有效率為97.14%;對照組的35例患者接受全身靜脈化療後的臨床總有效率為82.86%,差異有統計學意義(P<0.05);接受經支氣管鏡下跼部化療治療期間共髮生不良反應1例,佔5.71%;對照組的35例患者接受全身靜脈化療治療期間共髮生不良反應8例,佔22.86%,差異有統計學意義(P<0.05);生活質量評分明顯高于對照組35例接受全身靜脈化療後的生活質量評分(P<0.05). 結論 經支氣管鏡下跼部化療應用于中央型肺癌治療中的效果顯著,有效改善瞭患者的生活質量,值得推廣.
목적 본연구취경지기관경하국부화료응용우중앙형폐암치료중적림상개치진행료천현적연구화탐토,종이위림상상제공가고적수거.방법 선택아원자2012년1월~2014년1월수치적중앙형폐암환자70례,작위연구대상장기평균분위관찰조화대조조,량조환자균35례,관찰조행경지기관경하국부화료,대조조행전신정맥화료,재경과일개료정적치료후,대량조환자적기도협착치료효과,불량반응발생솔급생활질량평분진행관찰화통계.결과 관찰조적35례환자접수경지기관경하국부화료후적림상총유효솔위97.14%;대조조적35례환자접수전신정맥화료후적림상총유효솔위82.86%,차이유통계학의의(P<0.05);접수경지기관경하국부화료치료기간공발생불량반응1례,점5.71%;대조조적35례환자접수전신정맥화료치료기간공발생불량반응8례,점22.86%,차이유통계학의의(P<0.05);생활질량평분명현고우대조조35례접수전신정맥화료후적생활질량평분(P<0.05). 결론 경지기관경하국부화료응용우중앙형폐암치료중적효과현저,유효개선료환자적생활질량,치득추엄.
Objective To research and explore the clinical value of local chemotherapy under bronchoscopy in the treatment of central lung cancer so as to provide reliable data for clinic.Methods 70 patients with central lung cancer in our hospital who were admitted to our hospital from January 2012 to January 2014 were selected as the research objects and they were allocated to the observation group and the control group, with 35 in each. The observation group was received local chemotherapy under bronchoscopy while the control group was received systemic chemotherapy. After treatment of a course, curative effects of airway stenosis, the incidence rate of adverse reactions and score of life quality of patients in two groups were observed and recorded. Results The total clinical effective rate of 35 patients in the observation group who were received local chemotherapy under bronchoscopy was 97.14% while the total clinical effective rate of 35 patients in the control group who were received systemic chemotherapy was 82.86%. The difference of two groups was significant (P<0.05). 1 patient in the observation group had adverse reactions when receiving the treatment of local chemotherapy under bronchoscopy accounting for 5.71% and 8 patients in the control group had adverse reactions when receiving the treatment of systemic chemotherapy accounting for 22.86%. The difference of two groups was significant (P<0.05). Score of life quality of patients in the observation group was significantly higher than that of patients in the control group who were received systemic chemotherapy (P<0.05). Conclusion Application of local chemotherapy under bronchoscopy in the treatment of central lung cancer has a significant curative effect and effectively improves the life quality of patients which is worthy of promotion.
