现代诊断与治疗
現代診斷與治療
현대진단여치료
Modern Diagnosis & Treatment
2015年
14期
3121-3123
,共3页
刘志娟%陈咏鸽%张慧丽%巫雪芬
劉誌娟%陳詠鴿%張慧麗%巫雪芬
류지연%진영합%장혜려%무설분
氨基酸%早产儿%静脉营养血生化
氨基痠%早產兒%靜脈營養血生化
안기산%조산인%정맥영양혈생화
Amino acid%Premature infant%Venous nutrition blood biochemistry
目的 通过不同剂量氨基酸在早产儿早期静脉营养中的应用,探讨不同剂量氨基酸在早期静脉营养中对早产儿重要血生化指标的影响. 方法 将2013年3月~2014年6月收治的出生后24h内入院,出生体重1000~2000g的早产儿86例随机分成三组,分别早期静脉应用不同剂量氨基酸,低剂量组(EL)1g/kg·d),每天增加1.0g/kg,最大达3.5g/(kg·d);中剂量组(EM)2g/(kg·d),每天增加1g/kg,最大达3.7g/(kg·d),高剂量组(EH)3g/(kg·d),最大达4g/(kg· d),同时进行常规的其他静脉营养及肠内营养支持.结果 三组早产儿一般情况相似,重要血生化指标的比较,三组BUN在生后第7d差异有统计学意义,P<0.05,高剂量组一过性BUN升高明显多见;肌酐、pH值、碳酸氢盐、胆红素及并发症上差异无统计学意义,P>0.05. 结论 早产儿在生后24h内静脉应用氨基酸,3g/(kg·d),峰值达4g/(kg·d)有一过性BUN升高,这种升高在可耐受范围内.
目的 通過不同劑量氨基痠在早產兒早期靜脈營養中的應用,探討不同劑量氨基痠在早期靜脈營養中對早產兒重要血生化指標的影響. 方法 將2013年3月~2014年6月收治的齣生後24h內入院,齣生體重1000~2000g的早產兒86例隨機分成三組,分彆早期靜脈應用不同劑量氨基痠,低劑量組(EL)1g/kg·d),每天增加1.0g/kg,最大達3.5g/(kg·d);中劑量組(EM)2g/(kg·d),每天增加1g/kg,最大達3.7g/(kg·d),高劑量組(EH)3g/(kg·d),最大達4g/(kg· d),同時進行常規的其他靜脈營養及腸內營養支持.結果 三組早產兒一般情況相似,重要血生化指標的比較,三組BUN在生後第7d差異有統計學意義,P<0.05,高劑量組一過性BUN升高明顯多見;肌酐、pH值、碳痠氫鹽、膽紅素及併髮癥上差異無統計學意義,P>0.05. 結論 早產兒在生後24h內靜脈應用氨基痠,3g/(kg·d),峰值達4g/(kg·d)有一過性BUN升高,這種升高在可耐受範圍內.
목적 통과불동제량안기산재조산인조기정맥영양중적응용,탐토불동제량안기산재조기정맥영양중대조산인중요혈생화지표적영향. 방법 장2013년3월~2014년6월수치적출생후24h내입원,출생체중1000~2000g적조산인86례수궤분성삼조,분별조기정맥응용불동제량안기산,저제량조(EL)1g/kg·d),매천증가1.0g/kg,최대체3.5g/(kg·d);중제량조(EM)2g/(kg·d),매천증가1g/kg,최대체3.7g/(kg·d),고제량조(EH)3g/(kg·d),최대체4g/(kg· d),동시진행상규적기타정맥영양급장내영양지지.결과 삼조조산인일반정황상사,중요혈생화지표적비교,삼조BUN재생후제7d차이유통계학의의,P<0.05,고제량조일과성BUN승고명현다견;기항、pH치、탄산경염、담홍소급병발증상차이무통계학의의,P>0.05. 결론 조산인재생후24h내정맥응용안기산,3g/(kg·d),봉치체4g/(kg·d)유일과성BUN승고,저충승고재가내수범위내.
Objective The effects of different doses of amino acids on the important blood bio-chemical parameters of premature infants in early parenteral nutrition were discussed.Methods In March 2013 ~ 2014 June were born within 24 hours of admission, birth weight of 1000 ~ 2000g premature 86 cases were randomly divided into three groups, were early intravenous injection of different doses of amino acid, low dose group(EL)1g/kg·d) and daily increase of 1.0g/kg, the dada 3.5g/(kg·d), middle dose group (EM)2g/(kg·d) and daily increase of 1g/kg and the maximum 3.7g/(kg·d), the high dosage group (EH) 3g/(kg·d), the dada of 4g/(kg·d) and conventional other par-enteral nutrition and enteral nutrition support.Results The three groups of preterm infants gener-ally similar, important blood biochemical indexes, three groups of BUN in the 7d differences have were statistically significant (P<0.05), high dose group too of elevation of bun was significantly more; creatinine, pH, bicarbonate, bilirubin and complications were no were statistically significant (P>0.05).Conclusions The 24h in premature infants after intravenous administration of amino acids, 3g/kg·d), the peak value of 4g/kg.d) had an elevated BUN, which increased in the range of tolerance.
