CAJ | 학술논문

目的探讨射频消融(radiofrequency ablation,RFA)+经肝动脉栓塞化疗(transarterial chemoem-bolization,TACE)联合治疗较单纯RFA或单纯TACE对肝癌术后复发患者预后生存率的影响. 方法原发性肝癌术后有肝内复发而无肝外转移病例83例,按临床给予的治疗方案分为RFA组(A组),TACE组(B组),RFA+TACE联合组(C组),观察各组生存差异.结果 C组中位生存时间最长,(24.0±4.93)个月,B组次之,A组最短.累积生存率曲线显示C组生存率最高.A、B、C三组的0.5、1年生存率差异无统计学意义(P>0.05);2年生存率差异有统计学意义(P=0.041,P=0.030,均<0.05). 结论 RFA+TACE联合治疗较单纯RFA或TACE可以增加肝癌复发患者的2年生存时间,对肝癌术后复发患者是较好的选择.
목적 탐토사빈소융(radiofrequency ablation,RFA)+경간동맥전새화료(transarterial chemoem-bolization,TACE)연합치료교단순RFA혹단순TACE대간암술후복발환자예후생존솔적영향. 방법 원발성간암술후유간내복발이무간외전이병례83례,안림상급여적치료방안분위RFA조(A조),TACE조(B조),RFA+TACE연합조(C조),관찰각조생존차이.결과 C조중위생존시간최장,(24.0±4.93)개월,B조차지,A조최단.루적생존솔곡선현시C조생존솔최고.A、B、C삼조적0.5、1년생존솔차이무통계학의의(P>0.05);2년생존솔차이유통계학의의(P=0.041,P=0.030,균<0.05). 결론 RFA+TACE연합치료교단순RFA혹TACE가이증가간암복발환자적2년생존시간,대간암술후복발환자시교호적선택.
Objective To dissuss the outcomes of hepatocellular carcinoma (HCC) recurrence patients′survival through treatment of RFA+TACE compared with RFA or TACE alone. Methods The 83 recurrented patients with hepatocellular carcinoma were collected and divided according to clinical treatment regimes into A (RFA) group,B(TACE) group,C(RFA+TACE) group;survival difference was observed for each group. Results Group C had the longest median survival time,24.0 ±4.93 months,followed by group B,finally was group A. Cumulative survival curve showed the highest survival rate in Group C. The three groups of A,B,C 0.5-year,1-year survival rates had no statistically significant difference (P>0.05);the 2-year survival rate had significantly higher in group C than in group A,B,with a significant difference (P<0.05). Conclusion RFA+TACE combined therapy can increase the survival time of recurrented patients with HCC compared with RFA or TACE alone.