CAJ | 학술논문

目的:探讨炎性肌纤维母细胞瘤(IMT)的临床病理特征及鉴别诊断要点.方法:对5例IMT进行临床分析及光镜和免疫组化标记观察.结果:肿瘤由梭形肌纤维母细胞、纤维母细胞、大量慢性炎性细胞及黏液血管样背景构成.免疫组化示肿瘤细胞表达 vimentin、SMA、MSA,ALK 常阳性,CD34、desmin、CD10、calponin 和 actin 不同程度阳性(差异较大),CK或FV Ⅲ通常阴性.结论:炎性肌纤维母细胞瘤是一种少见肿瘤,少数具有复发倾向,易与其他梭形细胞肿瘤或瘤样病变混淆,诊断依赖于病理学检查和免疫组化染色.
목적:탐토염성기섬유모세포류(IMT)적림상병리특정급감별진단요점.방법:대5례IMT진행림상분석급광경화면역조화표기관찰.결과:종류유사형기섬유모세포、섬유모세포、대량만성염성세포급점액혈관양배경구성.면역조화시종류세포표체 vimentin、SMA、MSA,ALK 상양성,CD34、desmin、CD10、calponin 화 actin 불동정도양성(차이교대),CK혹FV Ⅲ통상음성.결론:염성기섬유모세포류시일충소견종류,소수구유복발경향,역여기타사형세포종류혹류양병변혼효,진단의뢰우병이학검사화면역조화염색.
Objective:To explore the clinicopathological features and differential diagnosis points of inflammatory myofibroblastic tumor(IMT).Methods:5 cases of IMT were carried on clinical analysis and light microscopy and immunohistochemical markers observation.Results:The tumor was composed of fusiform muscle fiber mother cell,fibroblasts,large number of chronic inflammatory cells and myxoid background with delicate vasculature.Immunohistochemistry showed that vimentin,SMA,MSA, ALK were positive in tumor cells,CD34,desmin,CD10,calponin and actin were different degrees of positive(with large difference), CK or FV Ⅲ was usually negative.Conclusion:Inflammatory myofibroblastic tumor was a rare tumor.The minority had the tendency of recurrence.It was easy to be confused with other spindle cell tumors or tumor-like lesions.its diagnosis depended on pathological examination and immunohistochemical staining.