CAJ | 학술논문

目的调查2011年1月至2013年12月山东地区急性呼吸道感染患者肺炎支原体感染情况.方法采用整群抽样方法收集2011年1月至2013年12月于山东大学附属省立医院就诊的22 946例急性呼吸道感染患者的血清,采用被动凝集法检测血清中的肺炎支原体抗体(肺炎支原体-IgM),并对不同年份、性别、年龄、季节患者的肺炎支原体感染情况进行统计分析.结果在22 946例急性呼吸道感染患者中,肺炎支原体阳性总数为7 632例,总阳性率为33.3％.2011年至2013年肺炎支原体阳性率分别为32.6％(2 385/7 306)、34.2％(2 337/6 840)及33.1％ (2 910/8 800),不同年份阳性率差异无统计学意义(P＞0.05).不同年龄患者间阳性率差异有统计学意义(P＜0.05),其中以7～12岁的阳性率最高,为46.9％(2 869/6 118);其次为13 ～ 20岁,为43.2％(326/755);再次为4～6岁,为38.8％ (2 476/6 384);＜1岁的婴儿阳性率最低,为7.8％(140/1 795).男性患者肺炎支原体阳性率为31.4％ (4 384/13 946),女性为36.1％(3 248/9 000),女性肺炎支原体阳性率明显高于男性,差异有统计学意义(P＜0.05).患者肺炎支原体阳性率以冬季(12-2月)最高,为39.9％(2 441/6 122);其次为秋季(9-11月),为37.8％(2 155/5 696);再次为春季(3-5月),为31.5％(1 565/4 975);夏季(6-8月)最低,为23.9％(1 471/6 153).3年来,秋、冬季肺炎支原体感染总阳性率明显高于夏季,差异有统计学意义(P＜0.05).结论 2011-2013年山东地区急性呼吸道感染患者的肺炎支原体阳性率稳定;女性高于男性;各年龄段均可感染,但以儿童和青少年易感;全年均可发病,但呈现季节性差异,以冬季的阳性率最高,夏季阳性率最低.
목적 조사2011년1월지2013년12월산동지구급성호흡도감염환자폐염지원체감염정황.방법 채용정군추양방법수집2011년1월지2013년12월우산동대학부속성립의원취진적22 946례급성호흡도감염환자적혈청,채용피동응집법검측혈청중적폐염지원체항체(폐염지원체-IgM),병대불동년빈、성별、년령、계절환자적폐염지원체감염정황진행통계분석.결과 재22 946례급성호흡도감염환자중,폐염지원체양성총수위7 632례,총양성솔위33.3％.2011년지2013년폐염지원체양성솔분별위32.6％(2 385/7 306)、34.2％(2 337/6 840)급33.1％ (2 910/8 800),불동년빈양성솔차이무통계학의의(P＞0.05).불동년령환자간양성솔차이유통계학의의(P＜0.05),기중이7～12세적양성솔최고,위46.9％(2 869/6 118);기차위13 ～ 20세,위43.2％(326/755);재차위4～6세,위38.8％ (2 476/6 384);＜1세적영인양성솔최저,위7.8％(140/1 795).남성환자폐염지원체양성솔위31.4％ (4 384/13 946),녀성위36.1％(3 248/9 000),녀성폐염지원체양성솔명현고우남성,차이유통계학의의(P＜0.05).환자폐염지원체양성솔이동계(12-2월)최고,위39.9％(2 441/6 122);기차위추계(9-11월),위37.8％(2 155/5 696);재차위춘계(3-5월),위31.5％(1 565/4 975);하계(6-8월)최저,위23.9％(1 471/6 153).3년래,추、동계폐염지원체감염총양성솔명현고우하계,차이유통계학의의(P＜0.05).결론 2011-2013년산동지구급성호흡도감염환자적폐염지원체양성솔은정;녀성고우남성;각년령단균가감염,단이인동화청소년역감;전년균가발병,단정현계절성차이,이동계적양성솔최고,하계양성솔최저.
Objective To investigate the infection situation of mycoplasma pneumonia (MP) in acute respiratory infection in Shandong Province from January 2011 to December 2013.Methods The serums of 22 946 patients with acute respiratory infection in Shandong Province from January 2011 to December 2013 were collected to measure the MP IgM.The distribution characteristics of MP infection in different years and seasons,different genders and ages,were analyzed.Results Among 22 946 samples,the total positive rate of MR was 33.3％ (7 632/22 946) ; the positive rate was 32.6％ (2 385/7 306),34.2％ (2 337/6 840) and 33.1％ (2 910/ 8 800) in 2011,2012 and 2013,respectively,showing no significant difference (P ＞ 0.05).The infection rate of MR was the highest in 7-12 years patients [46.9％ (2 869/6 118)],followed by 43.2％ (326/755) in 13-20 years old and 38.8％ (2 476/6 384) in 4-6 years old; the infection rate of MR was the lowest in ＜ 1 infants,[7.8％ (140/1 795)] ; there were significant differences among patients with different ages (P ＜ 0.05).The infection rate was 36.1％ (3 248/9 000) in females,higher than that in males [31.4％ (4 384/13 946)] (P ＜ 0.05).There were epidemiological differences of infection incidence of MP among different seasons:the infection rate in winter was the highest [39.9％ (2 441/6 122)],followed by 37.8％ (2 155/5 696) in autumn and 31.5％ (1 565/4 975) in spring; the infection rate in summer was the lowest [23.9％ (1 471/6 153)]; the infection rate in winter and autumn was significantly higher than that in summer (P ＜ 0.05).Conclusion The incidence of MP infection from 2011 to 2013 is stable in Shandong province; the females,children and adolescents are susceptible; the infection rate shows seasonal differences(highest in winter and lowest in summer).