中国医药
中國醫藥
중국의약
China Medicine
2015年
9期
1324-1326
,共3页
杨军%李井娜%郎海波%杨泽冉%张诗琪
楊軍%李井娜%郎海波%楊澤冉%張詩琪
양군%리정나%랑해파%양택염%장시기
非甾体消炎药%幽门螺杆菌%13C尿素呼气试验
非甾體消炎藥%幽門螺桿菌%13C尿素呼氣試驗
비치체소염약%유문라간균%13C뇨소호기시험
Non-steroidal antiinflammatory agents%Helicobacter pylori%13C-urea breath test
目的 了解北京城区长期服用非甾体消炎药(NSAID)患者幽门螺杆菌(Hp)感染现状,分析Hp感染的影响因素.方法 对190例北京城区长期服用NSAID患者行13C尿素呼气试验检查,统计Hp感染的比例,记录入选者的年龄、性别、吸烟史、饮酒史、文化程度、在职情况、胃炎及消化性溃疡家族史、饮食习惯资料,分析其与Hp感染的关系.结果 190例患者中,Hp阳性102例,占53.7％,阴性88例,占46.3％.不同年龄、在职情况、胃炎及消化性溃疡家族史和饮食习惯的患者Hp感染比例差异有统计学意义[＜40岁:60.0％(30/50),40～65岁:59.1％ (52/88),＞65岁:38.5％ (20/52);在职:80.0％ (80/100),不在职:24.4％ (22/90);有胃炎及消化性溃疡家族史:86.0％(74/86),无胃炎及消化性溃疡家族史:27.0％ (28/104);饮食规律:25.5％ (28/110),饮食不规律:92.5％ (74/80)] (P ＜0.05).结论 北京城区长期服用NSAID患者Hp感染与年龄、在职情况、胃炎及消化性溃疡家族史及饮食习惯明显相关.
目的 瞭解北京城區長期服用非甾體消炎藥(NSAID)患者幽門螺桿菌(Hp)感染現狀,分析Hp感染的影響因素.方法 對190例北京城區長期服用NSAID患者行13C尿素呼氣試驗檢查,統計Hp感染的比例,記錄入選者的年齡、性彆、吸煙史、飲酒史、文化程度、在職情況、胃炎及消化性潰瘍傢族史、飲食習慣資料,分析其與Hp感染的關繫.結果 190例患者中,Hp暘性102例,佔53.7％,陰性88例,佔46.3％.不同年齡、在職情況、胃炎及消化性潰瘍傢族史和飲食習慣的患者Hp感染比例差異有統計學意義[＜40歲:60.0％(30/50),40～65歲:59.1％ (52/88),＞65歲:38.5％ (20/52);在職:80.0％ (80/100),不在職:24.4％ (22/90);有胃炎及消化性潰瘍傢族史:86.0％(74/86),無胃炎及消化性潰瘍傢族史:27.0％ (28/104);飲食規律:25.5％ (28/110),飲食不規律:92.5％ (74/80)] (P ＜0.05).結論 北京城區長期服用NSAID患者Hp感染與年齡、在職情況、胃炎及消化性潰瘍傢族史及飲食習慣明顯相關.
목적 료해북경성구장기복용비치체소염약(NSAID)환자유문라간균(Hp)감염현상,분석Hp감염적영향인소.방법 대190례북경성구장기복용NSAID환자행13C뇨소호기시험검사,통계Hp감염적비례,기록입선자적년령、성별、흡연사、음주사、문화정도、재직정황、위염급소화성궤양가족사、음식습관자료,분석기여Hp감염적관계.결과 190례환자중,Hp양성102례,점53.7％,음성88례,점46.3％.불동년령、재직정황、위염급소화성궤양가족사화음식습관적환자Hp감염비례차이유통계학의의[＜40세:60.0％(30/50),40～65세:59.1％ (52/88),＞65세:38.5％ (20/52);재직:80.0％ (80/100),불재직:24.4％ (22/90);유위염급소화성궤양가족사:86.0％(74/86),무위염급소화성궤양가족사:27.0％ (28/104);음식규률:25.5％ (28/110),음식불규률:92.5％ (74/80)] (P ＜0.05).결론 북경성구장기복용NSAID환자Hp감염여년령、재직정황、위염급소화성궤양가족사급음식습관명현상관.
Objective To analyze the status and influence factors of helicobacter pylori (Hp) infection in patients taking non-steroidal antiinflammatory drugs (NSAID) in Beijing.Methods One hundred and ninety outpatients with long term usage of NSAID in Beijing were enrolled and underwent 13C-urea breath test (13 C-UBT).The proportion of Hp infection was calculated; the correlations of age,sex,smoking history,drinking history,education degree,working condition,family history of gastritis and peptic ulcer,dietary habits with Hp infection were analyzed.Results Among these 190 patients,there were 102 Hp positive patients (53.7％) and 88 Hp negative patients (46.3％).The infection rate of Hp was significantly different among patients with different ages,working conditions,family history of gastritis and peptic ulcer disease,dietary habits [＜ 40 years old:60.0％ (30/50),40-65 years old:59.1％ (52/88),＞65 years old:38.5％ (20/52) ; working:80.0％ (80/100),not working:24.4％ (22/90) ; positive family history:86.0％ (74/86),negative family history:27.0％ (28/104); regular diet:25.5％ (28/110),irregular diet:92.5％ (74/80)] (P ＜ 0.05).Conclusion The Hp infection in patients taking NSAID drugs for long time in Beijing is significantly related to age,working conditions,family history of gastritis and peptic ulcer and diet habits.
