实用医学杂志
實用醫學雜誌
실용의학잡지
The Journal of Practical Medicine
2015年
16期
2630-2633
,共4页
康祥锦%丁悦%杨洁%刘寒艳%杜红姿%刘见桥%安庚
康祥錦%丁悅%楊潔%劉寒豔%杜紅姿%劉見橋%安庚
강상금%정열%양길%류한염%두홍자%류견교%안경
辅助生殖技术%体外受精-胚胎移植%卵母细胞浆内单精子注射%畸形%多胎妊娠
輔助生殖技術%體外受精-胚胎移植%卵母細胞漿內單精子註射%畸形%多胎妊娠
보조생식기술%체외수정-배태이식%란모세포장내단정자주사%기형%다태임신
Assisted reproductive technologies%In vitro fertilization-embryo transfer%Single sperm Injection in oocytes%Congenital malformations%Multiple pregnancies
目的:比较体外受精-胚胎移植(IVF-ET)和单精子卵胞浆内注射(ICSI)的妊娠结局. 方法:回顾性分析2010年1月至2014年1月本中心接受辅助生殖技术助孕治疗的9 973个IVF-ET及1 368个ICSI-ET患者的临床资料,分别比较两组的着床率、妊娠率、多胎率、异位妊娠率、流产率、早产率、低出生体重儿率、先天畸形率. 结果:IVF 组与ICSI 组着床率 (33.42%,31.53%)、 妊娠率 (50.00% ,47.30%)、 早期流产率(13.93%,11.50%)、早产率(25.04%,23.26%)、性别比(115:100,103:100)、畸形率(1.05%,0.76%)均无统计学差异 (P > 0.05). IVF组的异位妊娠率 (3.75%,1.76%)、 多胎率 (38.54%,32.44%)、 低出生体重儿率(32.07%,26.86%)较ICSI 组均显著升高(P < 0.05 或P < 0.01). 结论:不同辅助生殖技术方法未明显增加妊娠风险,但常规IVF比ICSI的多胎率、异位妊娠率、低出生体重儿率更高.
目的:比較體外受精-胚胎移植(IVF-ET)和單精子卵胞漿內註射(ICSI)的妊娠結跼. 方法:迴顧性分析2010年1月至2014年1月本中心接受輔助生殖技術助孕治療的9 973箇IVF-ET及1 368箇ICSI-ET患者的臨床資料,分彆比較兩組的著床率、妊娠率、多胎率、異位妊娠率、流產率、早產率、低齣生體重兒率、先天畸形率. 結果:IVF 組與ICSI 組著床率 (33.42%,31.53%)、 妊娠率 (50.00% ,47.30%)、 早期流產率(13.93%,11.50%)、早產率(25.04%,23.26%)、性彆比(115:100,103:100)、畸形率(1.05%,0.76%)均無統計學差異 (P > 0.05). IVF組的異位妊娠率 (3.75%,1.76%)、 多胎率 (38.54%,32.44%)、 低齣生體重兒率(32.07%,26.86%)較ICSI 組均顯著升高(P < 0.05 或P < 0.01). 結論:不同輔助生殖技術方法未明顯增加妊娠風險,但常規IVF比ICSI的多胎率、異位妊娠率、低齣生體重兒率更高.
목적:비교체외수정-배태이식(IVF-ET)화단정자란포장내주사(ICSI)적임신결국. 방법:회고성분석2010년1월지2014년1월본중심접수보조생식기술조잉치료적9 973개IVF-ET급1 368개ICSI-ET환자적림상자료,분별비교량조적착상솔、임신솔、다태솔、이위임신솔、유산솔、조산솔、저출생체중인솔、선천기형솔. 결과:IVF 조여ICSI 조착상솔 (33.42%,31.53%)、 임신솔 (50.00% ,47.30%)、 조기유산솔(13.93%,11.50%)、조산솔(25.04%,23.26%)、성별비(115:100,103:100)、기형솔(1.05%,0.76%)균무통계학차이 (P > 0.05). IVF조적이위임신솔 (3.75%,1.76%)、 다태솔 (38.54%,32.44%)、 저출생체중인솔(32.07%,26.86%)교ICSI 조균현저승고(P < 0.05 혹P < 0.01). 결론:불동보조생식기술방법미명현증가임신풍험,단상규IVF비ICSI적다태솔、이위임신솔、저출생체중인솔경고.
Objective To compare the pregnancy outcomes of in vitro fertilization- embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI). Methods A retrospective analysis from January 2010 to January 2014 for 9 973 IVF-ET and 1 368 ICSI treatment cycles were collected. In the IVE and ICSI groups , we compared the implantation, clinical pregnancy, multiple pregnancy, ectopic pregnancy, abortion, premature birth, malformation rates, and sex ratio. Results The implantation rate (33.42%, 31.53%), clinical pregnancy rate (50.00%, 47.30%), abortion rate (13.93%, 11.50%), premature birth rate (25.04%, 23.26%), sex ratio (115:100, 103:100) and malformation rates (1.05%, 0.76%) were no statistically significant between the IVF-ET group and the ICSI group (P>0.05). The ectopic pregnancy rate (3.75%, 1.76%), multiple pregnancy rate (38.54%, 32.44%), low birth weight infants rate (32.07%, 26.86%) were increased significantly in the IVF group than the ICSI group (P<0.05 or P<0.01). Conclusions IVF and ICSI micromanipulation did not increase the risk of pregnancy. But the multiple pregnancy rate, ectopic pregnancy rate,low birth weight infants rate were increased significantly in the IVF group than the ICSI group.
