CAJ | 학술논문

目的：比较普拉洛芬滴眼液与妥布霉素地塞米松滴眼液控制翼状胬肉术后复发的临床疗效，提供更安全的防止翼状胬肉复发的药物方案。方法130例(154眼)接受手术治疗的翼状胬肉患者分为试验组(普拉洛芬滴眼液+玻璃酸钠滴眼液)和对照组(妥布霉素地塞米松滴眼液+玻璃酸钠滴眼液)，对两组角膜状况、眼压和翼状胬肉复发情况进行对比观察和统计学分析。结果随访3个月，对照组有9例(12眼)修正眼压高于正常上限值，与试验组0例(0眼)相比，差异有统计学意义(P<0．05)，余观察指标两组间差异无统计学意义(P>0．05)。结论普拉洛芬滴眼液控制翼状胬肉术后复发的疗效与妥布霉素地塞米松滴眼液相当，且更安全。
목적：비교보랍락분적안액여타포매소지새미송적안액공제익상노육술후복발적림상료효，제공경안전적방지익상노육복발적약물방안。방법130례(154안)접수수술치료적익상노육환자분위시험조(보랍락분적안액+파리산납적안액)화대조조(타포매소지새미송적안액+파리산납적안액)，대량조각막상황、안압화익상노육복발정황진행대비관찰화통계학분석。결과수방3개월，대조조유9례(12안)수정안압고우정상상한치，여시험조0례(0안)상비，차이유통계학의의(P<0．05)，여관찰지표량조간차이무통계학의의(P>0．05)。결론보랍락분적안액공제익상노육술후복발적료효여타포매소지새미송적안액상당，차경안전。
Objective To compare the efficacy of pranoprofen eye drops and tobramycin and dexamethasone ophthalmic on the controlling of postoperative recurrence in pterygium patients, to provide safer drug regimens to prevent the pterygium recur-rence. Methods From November 2010 to January 2014, 130 pterygium patients 154 eyes who underwent surgery in our hospital were divided into trial group( using pranoprofen eye drops) and control group( tobramycin and dexamethasone ophthalmic) , All pa-tients were followed up for 3 months( biweekly) and the conditions of cornea, intraocular pressure and postoperative recurrent were observed and compared between the two groups. Results Followed up for 3 months, there were 9 cases(12 eyes)with a higher in-traocular pressure in the control group, compared to trial group(0 cases of 0 eye), the difference was statistically significant(P<0. 05), but no difference in the other conditions(P>0. 05). Conclusion Pranoprofen eye drops is as effective as tobramycin and dexamethasone ophthalmic in preventing the recurrence of pterygium.