CAJ | 학술논문

脊髓损伤的治疗一直是世界性的难题，促进脊髓损伤后神经组织的修复，传统的手术和相应的辅助治疗并未取得突破性进展。组织工程学的发展，为神经组织的修复提供了良好的可能。被移植到患者脊髓损伤区域的干细胞，通过替换受损细胞、减少胶质瘢痕的形成、促进残存神经元细胞轴突再生及突触形成等，可促进脊髓形态及功能恢复。我们就目前应用干细胞治疗脊髓损伤的研究现状进行概述，并对其临床应用前景进行展望。
척수손상적치료일직시세계성적난제，촉진척수손상후신경조직적수복，전통적수술화상응적보조치료병미취득돌파성진전。조직공정학적발전，위신경조직적수복제공료량호적가능。피이식도환자척수손상구역적간세포，통과체환수손세포、감소효질반흔적형성、촉진잔존신경원세포축돌재생급돌촉형성등，가촉진척수형태급공능회복。아문취목전응용간세포치료척수손상적연구현상진행개술，병대기림상응용전경진행전망。
[Summary] Spinal cord injury is still a disease which is hard to cure in clinic and a project under research. The operation treatment and corresponding auxiliary treatment did not achieve a satisfied result. The cell-therapy of stem cells transplants to the patients' spinal cord injury area is a promising method. By the replacement of damaged cells, reducing the formation of glial scar, promoting the survival of neurons axonal regeneration and the synapse's formation, stem cell promote the recovery of function and morphology. In thispaper, the application of stem cell therapy in treating spinal cord injury was reviewed and prospected.