CAJ | 학술논문

目的：探讨2例骨上皮样血管内皮瘤（epithelioid hemangioendothelioma，EHE）的临床特点、治疗措施和预后因素。方法：回顾性分析2例原发于骨的 EHE 临床资料、诊断、治疗以及随访情况，并结合文献进行讨论。结果：2例骨 EHE 中男性和女性各1例，低度恶性的单发骨 EHE 患者经过局部病灶的放疗、TE 方案联合恩度等综合治疗，目前仍存活；侵袭性多发病灶的骨 EHE 患者经过 TE 方案联合恩度系统治疗、局部 TOMO等综合治疗，病情进展后死亡。结论：骨 EHE 的预后主要取决于肿瘤组织学级别和发生的部位；综合治疗可适当延长生存期，规范治疗尚无循证医学依据。
목적：탐토2례골상피양혈관내피류（epithelioid hemangioendothelioma，EHE）적림상특점、치료조시화예후인소。방법：회고성분석2례원발우골적 EHE 림상자료、진단、치료이급수방정황，병결합문헌진행토론。결과：2례골 EHE 중남성화녀성각1례，저도악성적단발골 EHE 환자경과국부병조적방료、TE 방안연합은도등종합치료，목전잉존활；침습성다발병조적골 EHE 환자경과 TE 방안연합은도계통치료、국부 TOMO등종합치료，병정진전후사망。결론：골 EHE 적예후주요취결우종류조직학급별화발생적부위；종합치료가괄당연장생존기，규범치료상무순증의학의거。
Objective:To investigate the clinicopathological characteristics,treatment and prognostic factor of the epithelioid hemangioendothelioma(EHE)derived from bone.Methods:Two cases of EHE in bone were retrospective-ly reviewed.Results:There were 1male and 1 female in the two cases.One case with low aggressive solitary EHE of the bone after radiotherapy,still alive.Another case with aggressive multifocal EHE of the bone after TE regimen com-bined with Endostar system treatment,TOMO radiotherapy and other comprehensive treatment,died after disease pro-gression.Conclusion:The prognosis of EHE derived from bone depends mainly on the tumor histological grade and site of occurrence.Comprehensive treatment can be appropriately extended survival time.There is no evidence -based medicine on specification of the treatment.