CAJ | 학술논문

目的：探讨新柏式薄层液基细胞学（TCT）联合 HPV －DNA 分型检测在宫颈癌筛查中的临床价值。方法：随机选取2011年4月－2014年4月于我院进行宫颈癌筛查的420例患者为研究对象。所有患者均进行 TCT 及 HPV －DNA 筛查，并同时进行宫颈组织活检进行最终确认。结果：TCT 筛查结果显示：ASCUS（意义不明的不典型鳞状细胞）患者为175例，阳性比例为41．7％。病理组织筛查结果显示：CINⅠ为199例，阳性比例为47．4％。HPV －DNA 共检出阳性患者180例，比例42．9％。临床症状越严重，HPV －DNA 阳性率越高。TCT 联合 HPV －DNA 筛查结果灵敏度较单独 TCT 和 HPV －DNA 筛查结果高，但特异性低，其阳性预测值和阴性预测值都较高，与病理结果筛查结果更为相似。结论：新柏式薄层液基细胞学（TCT）联合 HPV －DNA 分型检测在宫颈癌筛查中灵敏度高和准确性较高。
목적：탐토신백식박층액기세포학（TCT）연합 HPV －DNA 분형검측재궁경암사사중적림상개치。방법：수궤선취2011년4월－2014년4월우아원진행궁경암사사적420례환자위연구대상。소유환자균진행 TCT 급 HPV －DNA 사사，병동시진행궁경조직활검진행최종학인。결과：TCT 사사결과현시：ASCUS（의의불명적불전형린상세포）환자위175례，양성비례위41．7％。병리조직사사결과현시：CINⅠ위199례，양성비례위47．4％。HPV －DNA 공검출양성환자180례，비례42．9％。림상증상월엄중，HPV －DNA 양성솔월고。TCT 연합 HPV －DNA 사사결과령민도교단독 TCT 화 HPV －DNA 사사결과고，단특이성저，기양성예측치화음성예측치도교고，여병리결과사사결과경위상사。결론：신백식박층액기세포학（TCT）연합 HPV －DNA 분형검측재궁경암사사중령민도고화준학성교고。
Objective:To explore the clinical value of new type of TCT Parker combined with HPV -DNA typing in detecting cervical cancer screening.Methods:Randomly selected 420 cases of cervical cancer screening patients, all patients underwent TCT and HPV -DNA screening,while cervical biopsy for final confirmation.Results:CT screening showed number of patients with ASCUS 175 cases,the positive ratio 41.7%.Pathology screening showed ≥CINⅠ 199 cases,the positive ratio 47.4%.HPV -DNA positive patients,180 cases were detected,the proportion of 42.9%.The more severe the illness was,the higher the positive rate of HPV -DNA was.Conclusion:The new Parker style TCT combined HPV -DNA genotyping in cervical cancer screening is with high sensitivity and high accuracy.