基于调节Notch信号通路的Jagged1、 Sox17与脑缺血后血管新生的研究进展
기우조절Notch신호통로적Jagged1、 Sox17여뇌결혈후혈관신생적연구진전
Research Progress in Jagged1 and Sox17 Adjusting the Notch Signaling Pathway on Angiogenesis after Cerebral Ischemia
  • 万方数据
    国际老年医学杂志 국제노년의학잡지
    international Journal of Geriatrics
    2015年 5期 229-232,236 ,共5页

    孙江燕%刘轲%赵敏%刘昱言

    손강연%류가%조민%류욱언

    血管新生%Notch%Jagged1%Sox17%脑缺血 血管新生%Notch%Jagged1%Sox17%腦缺血
    혈관신생%Notch%Jagged1%Sox17%뇌결혈
    Angiogenesis%Notch%Jagged1%Sox17%Cerebral ischemia
    缺血性脑血管疾病的预后与血管新生关系密切。尖端细胞和茎细胞的动态平衡是保证血流灌注的关键。 Jag-ged1和Sox17介导的Nocth通路调节脑缺血后的功能性血管生成。本文将其近年研究进展做一综述。
    결혈성뇌혈관질병적예후여혈관신생관계밀절。첨단세포화경세포적동태평형시보증혈류관주적관건。 Jag-ged1화Sox17개도적Nocth통로조절뇌결혈후적공능성혈관생성。본문장기근년연구진전주일종술。
    The prognosis of ischemic cerebrovascular disease is closely related to angiogenesis. The dynamic equilibrium between tip cells and stalk cells is the key to ensure perfusion in the brain. Jagged1 and Sox17 regulate functional? angiogenesis after cerebral ischemia by mediating the Notch signaling pathway. In this paper the research progress in the above-metioned domain in recent years is reviewed.
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